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Merck
CN

P5338

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt

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Synonym(s):

5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine-4′,4″-disulfonic acid sodium salt, PDT disulfonate

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About This Item

Empirical Formula (Hill Notation):
C20H13N4NaO6S2
CAS Number:
69898-45-9
Molecular Weight:
492.46
NACRES:
NA.47
PubChem Substance ID:
24898624
UNSPSC Code:
12171500
EC Number:
274-196-3
MDL number:
MFCD00078417

Key Documents

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Product Name

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt, BioXtra

InChI key

ZGVNYCXXBQPDPQ-UHFFFAOYSA-M

InChI

1S/C20H14N4O6S2.Na/c25-31(26,27)15-8-4-13(5-9-15)18-19(14-6-10-16(11-7-14)32(28,29)30)23-24-20(22-18)17-3-1-2-12-21-17;/h1-12H,(H,25,26,27)(H,28,29,30);/q;+1/p-1

SMILES string

[Na+].OS(=O)(=O)c1ccc(cc1)-c2nnc(nc2-c3ccc(cc3)S([O-])(=O)=O)-c4ccccn4

product line

BioXtra

form

powder

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

mp

≥300 °C

anion traces

chloride (Cl-): ≤0.1%

cation traces

Al: ≤0.001%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.001%, Pb: ≤0.001%, Zn: ≤0.0005%

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Related Categories

General description

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt is also known as ferrozine.

Application

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt (ABTS) has been used in the ferene-s assay for the accurate determination of intracellular iron from iron oxide nanoparticles.
It has also been used in ABTS radical scavenging assay to determine the antioxidant activity of honey samples.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SHBP8767
SHBP7170
SHBN9450
SHBL4129
SHBL0802

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Marija Prezelj et al.
Clinical chemistry and laboratory medicine, 48(10), 1427-1432 (2010-08-14)
Non-transferrin-bound iron (NTBI) is a powerful promoter of free radical damage and highly toxic to biological systems, resulting in oxidative damage to proteins, lipids and DNA. This assay is based on the binding of serum NTBI by the chelator nitrilotriacetic
Dong-Ha Nam et al.
Aquatic toxicology (Amsterdam, Netherlands), 99(3), 351-359 (2010-06-15)
Brevetoxins are persistent, bioaccumulative, lipophilic polyether neurotoxins synthesized by Karenia brevis, a harmful algal bloom (HAB) dinoflagellate. Although some marine organisms accumulate potentially harmful levels of brevetoxins, little is known about neurotoxic effects in wild populations. Here, tissue (i.e., liver
Bruno Alies et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(4), 1161-1167 (2011-12-23)
The association constant of ferrozine (5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine-4,4''-disulfonic acid) with Cu(I) to form the chromophoric [Cu(I)(Fz)(2)](3-) complex was determined by UV/Vis titration experiments in Hepes buffer (0.1 M, pH 7.4). An association constant close to 10(12) M(-2), which is significantly weaker than
Ilkay Erdogan Orhan et al.
Natural product communications, 6(3), 375-378 (2011-04-13)
Ficus carica var. domestica Tsch. & Rav. (common fig) is widely grown in Turkey and exported for its edible fruits. In this study, the n-hexane, chloroform, acetone, methanol, n-butanol, and water extracts of the leaves of F. carica var. domestica
Aya Usami et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 24(6), 1217-1224 (2011-07-07)
Bovine milk α-casein was identified as a ferritin-binding protein, and ferritin is known to be a heme-binding protein. In this study, we found that the binding of α-casein to bovine spleen ferritin in vitro was blocked by hemin, but not
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