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P9422

Pramoxine hydrochloride

analytical standard, ≥98%

Synonym(s):

4-[3-(4-Butoxyphenoxy)propyl]morpholine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H27NO3 · HCl
CAS Number:
637-58-1
Molecular Weight:
329.86
NACRES:
NA.24
PubChem Substance ID:
329820349
UNSPSC Code:
41116107
EC Number:
211-293-1
MDL number:
MFCD00054323
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grade

analytical standard

Quality Level

100

assay

≥98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CCCCOc1ccc(OCCCN2CCOCC2)cc1

InChI

1S/C17H27NO3.ClH/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18;/h5-8H,2-4,9-15H2,1H3;1H

InChI key

SYCBXBCPLUFJID-UHFFFAOYSA-N

General description

Pramoxine hydrochloride is a surface and local anesthetic agent , which provides relief from itching and pain for a short period of time.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Topical anesthetic for skin or mucous membranes

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR9271
MKCK0443
MKBX9397V
MKBS0878V
SLBD7175V

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Rapid high-performance liquid chromatographic determination of pramoxine hydrochloride in topical cream and suppositories.
Z L Chang et al.
Journal of chromatography, 291, 428-433 (1984-05-18)
Effect of topical pramoxine on experimentally induced pruritus in humans.
G Yosipovitch et al.
Journal of the American Academy of Dermatology, 37(2 Pt 1), 278-280 (1997-08-01)
R Weinberger et al.
Journal of pharmaceutical sciences, 69(4), 475-477 (1980-04-01)
A rapid and quantitative method for the determination of pramoxine hydrochloride by high-pressure liquid chromatography is presented. The drug is extracted as the salt from a preparation with a high lipoid composition by partitioning it to the aqueous phase of
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Global Trade Item Number

SKUGTIN
P9422-25G04061833653081
P9422-10G04061834403081