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Merck
CN

P9422

Pramoxine hydrochloride

analytical standard, ≥98%

Synonym(s):

4-[3-(4-Butoxyphenoxy)propyl]morpholine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H27NO3 · HCl
CAS Number:
637-58-1
Molecular Weight:
329.86
NACRES:
NA.24
PubChem Substance ID:
329820349
UNSPSC Code:
41116107
EC Number:
211-293-1
MDL number:
MFCD00054323

Key Documents

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InChI key

SYCBXBCPLUFJID-UHFFFAOYSA-N

InChI

1S/C17H27NO3.ClH/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18;/h5-8H,2-4,9-15H2,1H3;1H

SMILES string

Cl.CCCCOc1ccc(OCCCN2CCOCC2)cc1

grade

analytical standard

assay

≥98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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General description

Pramoxine hydrochloride is a surface and local anesthetic agent , which provides relief from itching and pain for a short period of time.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Topical anesthetic for skin or mucous membranes

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR9271
MKCK0443
MKBX9397V
MKBS0878V
SLBD7175V

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Rapid high-performance liquid chromatographic determination of pramoxine hydrochloride in topical cream and suppositories.
Z L Chang et al.
Journal of chromatography, 291, 428-433 (1984-05-18)
Allergy to pramoxine (pramocaine).
W G van Ketel
Contact dermatitis, 7(1), 49-49 (1981-01-01)
I A Greer et al.
Scottish medical journal, 29(2), 104-106 (1984-04-01)
A double-blind randomised controlled trial, comparing pramoxine hydrochloride 1 per cent and hydrocortisone acetate 1 per cent in a mucoadhesive foam base, with simple aqueous foam (B.P.), in relieving episiotomy discomfort and episiotomy healing in 40 patients was carried out.
Canine and Feline Dermatology Drug Handbook (2012)
Uncovering tinea incognito. Topical corticosteroids can mask typical features of ringworm.
Carrie A Oklota et al.
Postgraduate medicine, 116(1), 65-66 (2004-07-28)
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