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Merck
CN

P9875

Phenolphthalein bisphosphate tetrasodium salt

≥92.5% purity, powder

Synonym(s):

Phenolphthalein diphosphate tetrasodium salt

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About This Item

Linear Formula:
C20H12O10P2Na4
CAS Number:
68807-90-9
Molecular Weight:
566.21
UNSPSC Code:
12171500
PubChem Substance ID:
329820357
NACRES:
NA.47
MDL number:
MFCD00005907

Key Documents

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Product Name

Phenolphthalein bisphosphate tetrasodium salt, ~95%

SMILES string

[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(OP([O-])([O-])=O)cc4

InChI

1S/C20H16O10P2.4Na/c21-19-17-3-1-2-4-18(17)20(28-19,13-5-9-15(10-6-13)29-31(22,23)24)14-7-11-16(12-8-14)30-32(25,26)27;;;;/h1-12H,(H2,22,23,24)(H2,25,26,27);;;;/q;4*+1/p-4

InChI key

HTMKLCRJVFFVDW-UHFFFAOYSA-J

assay

~95%

form

powder

impurities

Phenolphthalein, none detected
5-10% solvent (actual content on label)

solubility

water: 50 mg/mL, clear, colorless to faint yellow or tan

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

Quality Level

200

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Application

Phenolphthalein bisphosphate tetrasodium salt has been used as a component of modified Baird Parker (BP) agar to determine the expression of phosphatases of Staphylococcus aureus ATCC12600. It has also been used as a component of modified Tryptose phosphate/phenolphthalein/methyl green (M-TPMG) agar to detect enteroinvasive Escherichia coli (EIEC) apyrase activity.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000503886
0000503890
0000503883
0000503883
0000503890

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Ala160 and His116 residues are involved in activity and specificity of apyrase, an ATP-hydrolysing enzyme produced by enteroinvasive Escherichia coli
Serena Sarli
Microbiology (2005)
Phosphorylation controls the functioning of Staphylococcus aureus isocitrate dehydrogenase ? favours biofilm formation
U. Venkateswara Prasad
Journal of Enzyme Inhibition, 655-661 (2015)
U Venkateswara Prasad et al.
Journal of enzyme inhibition and medicinal chemistry, 30(4), 655-661 (2015-03-07)
Isocitrate dehydrogenase (IDH) gene from Staphylococcus aureus ATCC12600 was cloned, sequenced and characterized (HM067707). PknB site was observed in the active site of IDH; thus, it was predicted as IDH may be regulated by phosphorylation. Therefore, in this study, PknB

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