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PHR1010

Propylparaben

Name: Propylparaben
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):

Propyl 4-hydroxybenzoate, 4-Hydroxybenzoic acid propyl ester, Propyl paraben

Linear Formula:

HOC₆H₄CO₂CH₂CH₂CH₃

CAS Number:

94-13-3

Molecular Weight:

180.20

Beilstein:

1103245

EC Number:

202-307-7

MDL number:

MFCD00002354

PubChem Substance ID:

329823041

E Number:

E216

NACRES:

NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. P3650000
traceable to USP 1577008

API family

parabens

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

95-98 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCCOC(=O)c1ccc(O)cc1

InChI

1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3

InChI key

QELSKZZBTMNZEB-UHFFFAOYSA-N

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Related Categories

Analytical Reference Standards

Sigma-Aldrich

Certified Reference Materials

Food & Cosmetic Component Standards

Food Additive Standards

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Propylparaben is the benzoate ester, widely used as a preservative in personal care products.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2080 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Product No.

Description

Pricing

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

356.0 °F

Flash Point(C)

180 °C

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Effects of methylparaben, ethylparaben, and propylparaben on life parameters and sex ratio in the marine copepod Tigriopus japonicus.

Hye-Min Kang et al.

Chemosphere, 226, 388-394 (2019-04-05)

Parabens are used as a preservative substance in a wide range of man-made products causing deleterious effects on aquatic organisms and therefore, the concern of their effects to aquatic organisms has been increased. In this study, acute toxicity of methylparaben

Toxicological evaluation of three contaminants of emerging concern by use of the Allium cepa test.

O Herrero et al.

Mutation research, 743(1-2), 20-24 (2012-01-18)

Di(2-ethylhexyl)phthalate, triclosan and propylparaben are contaminants of emerging concern that have been subjected to extensive toxicological studies, but for which limited information is currently available concerning adverse effects on terrestrial plant systems. The Allium cepa test, which is considered one

Formation of organic nanoparticles by electrospinning of volatile microemulsions.

Michelle P Dvores et al.

Langmuir : the ACS journal of surfaces and colloids, 28(17), 6978-6984 (2012-03-29)

This study presents a method for one-step formation of poly(ethylene oxide) nanofibers incorporating nanoparticles of a poorly water-soluble compound. Using the new method reported here, nanofiber-nanoparticle composites are fabricated in one step by electrospinning of an oil-in-water microemulsion, in which

Food-grade antioxidants and antimicrobials to control growth and ochratoxin a production by Aspergillus section Nigri on peanut kernels.

C L Barberis et al.

Journal of food protection, 73(8), 1493-1501 (2010-09-08)

Each year, a significant portion of the peanuts produced cannot be marketed because of fungal disease at the postharvest stage and mycotoxin contamination. Antioxidants could be used as an alternative to fungicides to control ochratoxigenic fungi in peanuts during storage.

Degradation of parabens by Pseudomonas beteli and Burkholderia latens.

Aeshna Amin et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 75(2), 206-212 (2010-03-09)

p-Hydroxybenzoic acid esters (parabens) are commonly used antimicrobial preservatives in pharmaceutical formulations. Two microorganisms, isolated from non-sterile methyl paraben (MP) and propyl paraben (PP) solutions, were found to degrade the respective parabens. Identification by 16S rRNA partial gene sequencing revealed

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