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PHR1152

Phenyl salicylate melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Phenyl salicylate, Salol

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About This Item

Linear Formula:
2-(HO)C6H4CO2C6H5
CAS Number:
118-55-8
Molecular Weight:
214.22
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823170
EC Number:
204-259-2
Beilstein/REAXYS Number:
393969
MDL number:
MFCD00002213
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Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1534209

API family

phenyl salicylate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

172-173 °C/12 mmHg (lit.)

mp

~Approximately 42 °C, 41-43 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Oc1ccccc1C(=O)Oc2ccccc2

InChI

1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H

InChI key

ZQBAKBUEJOMQEX-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Phenyl salicylate is a phenyl ester of salicylic acid and is used as a medicine under the name ′salol′ as an internal antiseptic. It finds its application in paints, waxes, and varnishes as it is found to absorb UV radiation in the range of 290-325 nm. It also shows its presence in cosmetics and sunscreens as a UV filter.

Application

Phenyl salicylate may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7176 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.

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pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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