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Merck
CN

PHR1201

Supelco

Resorcinol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Resorcinol, 1,3-Benzenediol

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About This Item

Linear Formula:
C6H4-1,3-(OH)2
CAS Number:
108-46-3
Molecular Weight:
110.11
Beilstein:
906905
EC Number:
203-585-2
MDL number:
MFCD00002269
UNSPSC Code:
41116107
PubChem Substance ID:
329823208
NACRES:
NA.24

Key Documents

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grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. Y0000767
traceable to USP 1602003

vapor density

3.8 (vs air)

vapor pressure

1 mmHg ( 21.1 °C)

API family

resorcinol

CofA

current certificate can be downloaded

autoignition temp.

1126 °F

packaging

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

178 °C/16 mmHg (lit.)

mp

109-112 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Oc1cccc(O)c1

InChI

1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H

InChI key

GHMLBKRAJCXXBS-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Resorcinol, a dihydric phenol, is a key component of hair dyeing products. It is widely used as an antiseptic and reduces pain from painful nodules in patients suffering from Hidradenitis suppurativa (HS).

Application

Resorcinol may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using first-derivative UV spectrophotometric technique and capillary zone electrophoresis.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter P500201 in the slot below. This is an example certificate only and may not be the lot that you receive.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 1 Oral - STOT SE 2 Oral

Target Organs

Central nervous system,Blood, Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

260.6 °F - closed cup

Flash Point(C)

127 °C - closed cup

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous determination of methylene blue, hexamethylene tetramine and resorcinol in pharmaceutical formulations by first-derivative UV spectrophotometry
Onur F and Acar N
International Journal of Pharmaceutics, 78(1), 89-91 (1992)
Determination of phenol, resorcinol and hydroquinone in air samples by synchronous fluorescence using partial least-squares (PLS).
Pistonesi MF, et al.
Talanta, 69(5), 1265-1268 (2006)
Simultaneous determination of cloramphenicol, salicylic acid and resorcinol by capillary zone electrophoresis and its application to pharmaceutical dosage forms
Gomez RM, et al.
Talanta, 61(2), 233-238 (2003)

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