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PHR1225

Supelco

3-Aminophenol

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
m-Aminophenol
Linear Formula:
H2NC6H4OH
CAS Number:
591-27-5
Molecular Weight:
109.13
Beilstein:
636059
EC Number:
209-711-2
MDL number:
MFCD00007786
PubChem Substance ID:
329823231
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1026004

API family

paracetamol, mesalazine, acetaminophen

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

164 °C/11 mmHg (lit.)

mp

120-124 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Nc1cccc(O)c1

InChI

1S/C6H7NO/c7-5-2-1-3-6(8)4-5/h1-4,8H,7H2

InChI key

CWLKGDAVCFYWJK-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA9037 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302 + H332 - H319 - H411

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Regulatory Information

危险化学品

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U Lechner et al.
Journal of basic microbiology, 28(9-10), 629-637 (1988-01-01)
The bacterial strain mA3 capable of utilizing 3-aminophenol as the sole source of carbon, energy and nitrogen for growth was isolated from an enrichment culture and identified as an Arthrobacter species. Utilization of 0.68 mg/ml 3-aminophenol by batch cultures of
Hsiao-Shu Lee et al.
The Annals of occupational hygiene, 53(3), 289-296 (2009-03-13)
Skin irritation and contact allergies are skin disorders common to hairdressers. The predominant oxidative hair dye components, such as p-phenylenediamine (PPD) and aminophenol isomers, can cause contact dermatitis. Use of protective gloves can prevent dermal contact with skin irritants. This
Suresh Chandra Rastogi et al.
Contact dermatitis, 55(2), 95-100 (2006-08-26)
Contact allergy to hair dye ingredients, especially precursors and couplers, is a well-known entity among consumers having hair colouring done at home or at a hairdresser. The aim of the present investigation was to estimate consumer exposure to some selected
E Vasbinder et al.
Biomedical chromatography : BMC, 18(1), 55-63 (2004-02-12)
An ion-pair high performance liquid chromatographic method was developed for the simultaneous determination of p-aminosalicylic acid (PAS) and its degradation product m-aminophenol (MAP) in a newly developed multiparticular drug delivery system. Owing to the concentration differences of PAS and MAP
O I Malykhina et al.
Sudebno-meditsinskaia ekspertiza, 49(1), 25-27 (2006-03-03)
The article presents the results of nitrobenzene and 3-aminohydroxibensene extraction from aqueous solutions by means of five organic solvents. The following factors influence on the extraction degree is shown: the nature of the extracting agent, aqueous phase pH, saturation of
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