Skip to Content
Merck
CN

PHR1226

Cetylpyridinum chloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Cetylpyridinium chloride monohydrate, 1-Hexadecylpyridinium chloride, Hexadecylpyridinium chloride monohydrate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C21H38ClN · H2O
CAS Number:
6004-24-6
Molecular Weight:
358.00
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823232
EC Number:
204-593-9
Beilstein/REAXYS Number:
3578606
MDL number:
MFCD00149977

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Cetylpyridinum chloride, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C21H38N.ClH.H2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H;1H2/q+1;;/p-1

InChI key

NFCRBQADEGXVDL-UHFFFAOYSA-M

SMILES string

O.[Cl-].CCCCCCCCCCCCCCCC[n+]1ccccc1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. C1000000
traceable to USP 1104006

API family

cetylpyridinium

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

83-86 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

Looking for similar products? Visit Product Comparison Guide

Related Categories

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

Cetylpyridinum chloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical preparations using reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Cetylpyridinum chloride is a quaternary ammonium compound and an active ingredient of antiseptic oral mouth rinses with broad spectrum antimicrobial activity. Its mode of action involves a rapid bactericidal effect on Gram-positive pathogens and a fungicide effect on certain yeasts.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0149 in the slot below. This is an example certificate only and may not be the lot that you receive.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Efficacy of cetylpyridinium chloride used as oropharyngeal antiseptic
Pitten A-F and Kramer A
Journal of Pharmaceutical and Biomedical Analysis, 51(07), 588-595 (2001)
Pharmaceutical Emulsions and Suspensions: Second Edition, Revised and Expanded
Drugs and the Pharmaceutical Sciences (2000)
Determination of cetylpyridinium chloride and tetracaine hydrochloride in buccal tablets by RP-HPLC
Wang J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 32(2), 381-386 (2003)
Kwang Sik Suh et al.
Cytotechnology, 66(6), 925-935 (2013-10-12)
Achyranthes bidentata (A. bidentata) Blume is a medicinal herb with the property of strengthening bones and muscles and ensuring proper downward flow of blood in terms of the therapeutic theory of traditional medicine. In the present study, the effect of
Dong Suk Yoon et al.
Stem cells (Dayton, Ohio), 32(12), 3219-3231 (2014-08-19)
SOX2 is crucial for the maintenance of the self-renewal capacity and multipotency of mesenchymal stem cells (MSCs); however, the mechanism by which SOX2 is regulated remains unclear. Here, we report that RNA interference of sirtuin 1 (SIRT1) in human bone
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service