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PHR1275

Naphthalene

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Naphthalene

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About This Item

Empirical Formula (Hill Notation):
C10H8
CAS Number:
91-20-3
Molecular Weight:
128.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823271
EC Number:
202-049-5
Beilstein/REAXYS Number:
1421310
MDL number:
MFCD00001742

Key Documents

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Product Name

Naphthalene, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H

SMILES string

c1ccc2ccccc2c1

InChI key

UFWIBTONFRDIAS-UHFFFAOYSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1457083

vapor density

4.4 (vs air)

vapor pressure

0.03 mmHg ( 25 °C)

CofA

current certificate can be downloaded

autoignition temp.

978 °F

expl. lim.

5.9 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

218 °C (lit.)

mp

80-82 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Other Notes

To see an example of a Certificate of Analysis for this material enter LRAA0011 in the slot below. This is an example certificate only and may not be the lot that you receive.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Naphthalene is produced from fossil fuels such as coal and petroleum. Its commercial applications include, the production of polyvinyl plastics, moth repellents, dyes, leather tanning agents, resins, etc.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

173.3 °F - closed cup

flash_point_c

78.5 °C - closed cup

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Toxicological Profile for Naphthalene, 1-methylnaphthalene, and 2-methylnaphthalene (2005)
Fabrice Gritti et al.
Journal of chromatography. A, 1352, 20-28 (2014-06-14)
The effect of the pressure on the dispersion of a low molecular weight compound along 0.508 and 1.016 mm i.d. × 50 cm long open circular tubes was investigated theoretically and experimentally. The theoretical predictions were based on the early
H Höke et al.
Toxicology, 126(1), 1-7 (1998-05-19)
Detailed knowledge does exist on the toxicological safety of diisopropylnaphthalene (DIPN). Its metabolism is the key to understanding its very low toxicity. The metabolic pathway of 2,6-DIPN in rats was found to proceed almost exclusively through oxidation of the isopropyl
Chunrong Jia et al.
International journal of environmental research and public health, 7(7), 2903-2939 (2010-08-19)
Both the recent classification of naphthalene as a possible human carcinogen and its ubiquitous presence motivate this critical review of naphthalene's sources and exposures. We evaluate the environmental literature on naphthalene published since 1990, drawing on nearly 150 studies that
Lorenz R Rhomberg et al.
Critical reviews in toxicology, 40(8), 671-696 (2010-08-21)
Human health risk assessment consists of bringing to bear a large body of in vitro, animal, and epidemiologic studies on the question of whether environmental exposures to a substance are a potential risk to humans. The body of scientific information
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