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PHR1320

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Residual Solvent - Acetonitrile

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Acetonitrile, ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
Linear Formula:
CH3CN
CAS Number:
75-05-8
Molecular Weight:
41.05
Beilstein:
741857
EC Number:
200-664-3
MDL number:
MFCD00001878
PubChem Substance ID:
329823305
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1601340

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

973 °F

expl. lim.

16 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

density

0.786 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-30°C

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Acetonitrile is a CRM and Secondary Pharmaceutical Reference Standard, traceable and qualified against the corresponding Pharmacopeial standards. Sigma-Aldrich offers Fluka brand Certified Reference Materials (CRMs) for the analysis of Residual Solvents. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA0679 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

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