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PHR1328

Supelco

Magnesium carbonate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Magnesium carbonate hydrate, Magnesium carbonate
Linear Formula:
MgCO3 · x H2O
CAS Number:
Molecular Weight:
84.31 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to USP 1374226

storage temp.

2-30°C

SMILES string

O.[Mg++].[O-]C([O-])=O

InChI

1S/CH2O3.Mg.H2O/c2-1(3)4;;/h(H2,2,3,4);;1H2/q;+2;/p-2

InChI key

OUHCLAKJJGMPSW-UHFFFAOYSA-L

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Magnesium carbonate is a naturally occurring magnesium salt. Magnesium carbonate can be prepared synthetically and is widely used in paints, printing ink, table salt and also as an antacid. It is also used in cosmetics as a colorling agent, perfume carrier and also as an anticaking agent.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC4013 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

A Consumerys Dictionary of Household, Yard and Office Chemicals: Complete Information About Harmful and Desirable Chemicals Found in Everyday Home Products, Yard Poisons, and Office Polluters (2007)
Handbook of Fillers, Extenders, and Diluents (2007)
A Consumerys Dictionary of Household, Yard and Office Chemicals: Complete Information About Harmful and Desirable Chemicals Found in Everyday Home Products, Yard Poisons, and Office Polluters (2007)
Ronak B Shah et al.
Journal of controlled release : official journal of the Controlled Release Society, 196, 60-70 (2014-09-16)
A biomimetic approach to organic solvent-free microencapsulation of proteins based on the self-healing capacity of poly (DL)-lactic-co-glycolic acid (PLGA) microspheres containing glycosaminoglycan-like biopolymers (BPs), was examined. To screen BPs, aqueous solutions of BP [high molecular weight dextran sulfate (HDS), low
Johanna Mosig et al.
Journal of pharmaceutical sciences, 104(3), 1108-1118 (2015-01-07)
The influence of lubrication and particle size on the reduced compactability after dry granulation was investigated. Powder cellulose, lactose, magnesium carbonate, and two types of microcrystalline cellulose were roll compacted, granulated, and sieved into particle fractions. Particle fractions were compressed

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