Merck
CN
All Photos(1)

Documents

PHR1454

Supelco

Arginine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
L-Arginine monohydrochloride, (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
1119-34-2
Molecular Weight:
210.66
Beilstein:
3631658
EC Number:
214-275-1
MDL number:
MFCD00064550
PubChem Substance ID:
329822614
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to BP 694
traceable to Ph. Eur. A1271000
traceable to USP 1042601

API family

arginine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

236-230 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Arginine Hydrochloride is a salt of arginine, which is a semi-essential amino acid. This dibasic amino acid acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Arginine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, dietary supplements and capsules by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3002 in the slot below. This is an example certificate only and may not be the lot that you receive.

related product

Product No.
Description
Pricing

PHR1106

L-Arginine, Pharmaceutical Secondary Standard; Certified Reference Material

A1271000

Arginine hydrochloride, European Pharmacopoeia (EP) Reference Standard

A1270000

Arginine, European Pharmacopoeia (EP) Reference Standard

Y0000304

Arginine aspartate, European Pharmacopoeia (EP) Reference Standard

1042500

L-Arginine, United States Pharmacopeia (USP) Reference Standard

1042554

Arginine ethyl ester dihydrochloride, United States Pharmacopeia (USP) Reference Standard

1042601

Arginine hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP694

Arginine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2813

Arginine aspartate, certified reference material, pharmaceutical secondary standard

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Arginine Hydrochloride
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 44(5), 366-366 (2018)
Quantification of arginine in dietary supplement tablets and capsules by silica gel high-performance thin-layer chromatography with visible mode densitometry
Hess B and Sherma J
Acta Chromatographica , 60-69 (2004)
Nivaldo Ribeiro Villela et al.
Journal of translational medicine, 12, 232-232 (2014-08-26)
Relative hypovolemia is frequently found in early stages of severe sepsis and septic shock and prompt and aggressive fluid therapy has become standard of care improving tissue perfusion and patient outcome. This paper investigates the role of the nitric oxide
Jenna Gallie et al.
PLoS biology, 13(3), e1002109-e1002109 (2015-03-13)
Phenotype switching is commonly observed in nature. This prevalence has allowed the elucidation of a number of underlying molecular mechanisms. However, little is known about how phenotypic switches arise and function in their early evolutionary stages. The first opportunity to
X Zheng et al.
Journal of dental research, 94(2), 344-353 (2014-12-06)
Dental caries is closely associated with the microbial disequilibrium between acidogenic/aciduric pathogens and alkali-generating commensal residents within the dental plaque. Fluoride is a widely used anticaries agent, which promotes tooth hard-tissue remineralization and suppresses bacterial activities. Recent clinical trials have
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service