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PHR1479

Erythritol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

meso-Erythritol, 1,2,3,4-Butanetetrol, meso-1,2,3,4-Tetrahydroxybutane, i-Erythritol

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About This Item

Linear Formula:
HOCH2[CH(OH)]2CH2OH
CAS Number:
149-32-6
Molecular Weight:
122.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823407
EC Number:
205-737-3
Beilstein/REAXYS Number:
1719753
MDL number:
MFCD00004710

Key Documents

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Product Name

Erythritol, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

UNXHWFMMPAWVPI-ZXZARUISSA-N

InChI

1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4+

SMILES string

OC[C@@H](O)[C@@H](O)CO

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000477
traceable to USP 1241903

API family

erythritol

CofA

current certificate can be downloaded

packaging

ampule of 1 × 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

329-331 °C (lit.)

mp

118-120 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

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Application

Erythritol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Allelic variation of the Tas1r3 gene affects behavioral taste responses to this sugar alcohol, suggesting that it is a T1R3 receptor ligand.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAA3027 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The influence of fine excipient particles on the performance of carrier-based dry powder inhalation formulations.
Jones MD and Price R
Pharmaceutical Research, 23(8), 1665-1674 (2006)
An investigation into the dispersion mechanisms of ternary dry powder inhaler formulations by the quantification of interparticulate forces.
Jones MD, et al.
Pharmaceutical Research, 25(2), 337-348 (2008)

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