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PHR1569

Levocarnitine

Name: Levocarnitine
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

L-Carnitine inner salt, (−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin B_T

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About This Item

Linear Formula:

(CH₃)₃N⁺CH₂CH(OH)CH₂COO^-

CAS Number:

541-15-1

Molecular Weight:

161.20

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823478

EC Number:

208-768-0

Beilstein/REAXYS Number:

4292315

MDL number:

MFCD00038747

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Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. L0399900, traceable to USP 1359903

API family

levocarnitine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

197-212 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C[N+](C)(C)C[C@H](O)CC([O-])=O

InChI

1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1

InChI key

PHIQHXFUZVPYII-ZCFIWIBFSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Levocarnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

To see an example of a Certificate of Analysis for this material enter LRAB7787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c