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PHR1701

Triamcinolone Acetonide

Name: Triamcinolone Acetonide
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Triamcinolone acetonide, 9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide

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About This Item

Empirical Formula (Hill Notation):

C₂₄H₃₁FO₆

CAS Number:

76-25-5

Molecular Weight:

434.50

NACRES:

NA.24

PubChem Substance ID:

329823564

UNSPSC Code:

41116107

EC Number:

200-948-7

MDL number:

MFCD00056834

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Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. T1900000, traceable to USP 1677002

API family

triamcinolone

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

Gene Information

human ... NR3C1(2908)

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Triamcinolone Acetonide is a glucocorticoid and a derivative of pregnane, used mainly in the treatment of rheumatic disease, allergic and dermatologic symptoms.

Application

Triamcinolone Acetonide may be used as a pharmaceutical standard for the determination of the analyte in drug dosage forms by high performance liquid chromatography and spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC2813 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H360

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous determination of terbinafine HCL and triamcinolone acetonide by UV derivative spectrophotometry and spectrodensitometry.

El-Saharty YS, et al.

Journal of Pharmaceutical and Biomedical Analysis, 28(3-4), 569-580 (2002)

Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC.

Matysova L, et al.

Analytical and Bioanalytical Chemistry, 376(4), 440-443 (2003)

Triamcinolone acetonide.

Jeal W and Faulds D

Drugs, 53(2), 257-280 (1997)

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Global Trade Item Number

SKU	GTIN
PHR1701-1G	04061835238187