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PHR1744

Supelco

3-Chlorobenzoic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
3-Chlorobenzoic acid
Linear Formula:
ClC6H4CO2H
CAS Number:
Molecular Weight:
156.57
Beilstein:
907218
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 200 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

153-157 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to USP 1112299

storage temp.

2-30°C

SMILES string

OC(=O)c1cccc(Cl)c1

InChI

1S/C7H5ClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H,9,10)

InChI key

LULAYUGMBFYYEX-UHFFFAOYSA-N

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General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
3-Chlorobenzoic acid may be used as a pharmaceutical reference standard for the determination of the analyte in bulk powders and pharmaceutical formulations by chromatography.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7967 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificate of Analysis

Certificate of Origin

Kinetic study and peak purity determination of bupropion hydrochloride using RRLC/DAD and HPLC/MWD methods: stability study and application in pharmaceutical preparation and in synthetic mixtures with nicotine
El-Kosasy AM, et al.
Royal Society of Chemistry Advances, 5(79), 64274-64285 (2015)
Stability indicating HPLC and spectrophotometric methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates and related impurity
Abbas SS, et al.
Bulletin of Faculty of Pharmacy, Cairo University , 50(1), 49-59 (2012)

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