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Merck
CN

PHR1905

Citalopram Related Compound G

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

5-Chloro-1-(4-fluorophenyl)-1,3-dihydro-N,N-dimethyl-1-isobenzofuranpropanamine hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C19H21ClFNO · HBr
CAS Number:
1332724-08-9
Molecular Weight:
414.74
NACRES:
NA.24
UNSPSC Code:
41116107

Key Documents

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grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1134197

API family

citalopram

CofA

current certificate can be downloaded

packaging

pkg of 25 mg

application(s)

pharmaceutical

format

neat

storage temp.

2-30°C

Quality Level

300

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Citalopram Related Compound G is a related impurity found in the drug Citalopram. Citalopram is a racemic bicyclic phthalane derivative and is a potent anti-depressant drug, that acts by inhibition of serotonin uptake.

Application

Citalopram Related Compound G may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB2757 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Citalopram Hydrobromide
USP42/NF37
United States Pharmacopeia/National Formulary, 39(6), 1018-1018 (2018)
Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS
Raman B, et al.
Journal of Pharmaceutical and Biomedical Analysis, 50(3), 377-383 (2009)

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