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COO/COA

PHR2009

Allopurinol Related Compound E

Name: Allopurinol Related Compound E
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):

Ethyl 3-(formylamino)-1H-pyrazole-4-carboxylate, Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate

Empirical Formula (Hill Notation):

C₇H₉N₃O₃

CAS Number:

31055-19-3

Molecular Weight:

183.16

NACRES:

NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to BP 845
traceable to Ph. Eur. A0350050
traceable to USP 1013068

API family

allopurinol

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

InChI

1S/C7H9N3O3/c1-2-13-7(12)5-3-9-10-6(5)8-4-11/h3-4H,2H2,1H3,(H2,8,9,10,11)

InChI key

VAEIHNPPOAVFAR-UHFFFAOYSA-N

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Related Categories

Analytical Reference Standards

Certified Reference Materials

Pharmacopeia & Metrological Institute Standards

General description

Allopurinol Related Compound E is an impurity of allopurinol. Allopurinol is a purine analog and a structural isomer of the naturally available purine in the body, hypoxanthine. It is also a powerful xanthine oxidase inhibitor. It is widely utilized against purine and pyrimidine metabolic disorders that give rise to an excess of uric acid in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Allopurinol Related Compound E may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7871 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

related product

Product No.

Description

Pricing

1013035

1013046

1013013

1013024

1013079

BP870

Allopurinol, British Pharmacopoeia (BP) Reference Standard

PHR2005

PHR2006

PHR2007

PHR2008

BP832

Allopurinol impurity B, British Pharmacopoeia (BP) Reference Standard

BP844

Allopurinol impurity D, British Pharmacopoeia (BP) Reference Standard

BP845

Allopurinol impurity E, British Pharmacopoeia (BP) Reference Standard

BP843

Allopurinol impurity C, British Pharmacopoeia (BP) Reference Standard

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Development of a stability indicating RP-RRLC method for determination of allopurinol and its degradation products in solid oral dosage

Singh S and Gadhawala Z

International Journal of PharmTech Research, 5(1), 44-53 (2013)

Allopurinol

USP42-NF37: United States Pharmacopeia and National Formulary

United States Pharmacopeia/National Formulary, 34(1), 132-132 (2018)

High-performance liquid chromatography with polarographic and voltammetric anodic detection: simultaneous determination of allopurinol, oxipurinol and uric acid in body fluids

Palmisano F, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 306(1), 205-214 (1984)

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