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PHR2155

Cortisone

Name: Cortisone
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Cortisone, 17α,21-Dihydroxy-4-pregnene-3,11,20-trione, 17α-Hydroxy-11-dehydrocorticosterone, 4-Pregnene-17α,21-diol-3,11,20-trione, Kendall’s Compound E, Reichstein’s Substance Fa

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₈O₅

CAS Number:

53-06-5

Molecular Weight:

360.44

NACRES:

NA.24

UNSPSC Code:

41116107

Beilstein/REAXYS Number:

1356062

MDL number:

MFCD00003610

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Properties

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1149999

API family

cortisone

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

mp

223-228 °C (dec.) (lit.)

application(s)

pharmaceutical
pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

-10 to -25°C

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)CC(=O)[C@H]23

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

InChI key

MFYSYFVPBJMHGN-ZPOLXVRWSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB9885 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Pictograms

GHS08

Signal Word

Warning

Hazard Codes

H361d

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)