Skip to Content
Merck
CN

PHR3251

Tolbutamide

pharmaceutical secondary standard, certified reference material

Synonym(s):

Tolbutamide, 1-Butyl-3-(4-methylphenylsulfonyl)urea, N-[(Butylamino)carbonyl]-4-methylbenzenesulfonamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H18N2O3S
CAS Number:
64-77-7
Molecular Weight:
270.35
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
1984428
MDL number:
MFCD00027169

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Tolbutamide, pharmaceutical secondary standard, certified reference material

SMILES string

CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)

InChI key

JLRGJRBPOGGCBT-UHFFFAOYSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1670003

API family

tolbutamide

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

application(s)

pharmaceutical

storage temp.

2-30°C

Quality Level

300

Looking for similar products? Visit Product Comparison Guide

Related Categories

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Biochem/physiol Actions

Anti-diabetic agent. Metabolized by CYP2C9 (tolbutamide hydroxylase).

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Tolbutamide can be used as a reference compound for the determination of torasemide in human plasma and 6-hydroxykynurenic acid in rat plasma by the LC-MS/MS method. It can also be used for the quantification of analytes in human plasm.

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service