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Merck
CN

PMC1105

Methanol

≥99.75%, ISOM8, anhydrous

Synonym(s):

Dry Methanol, MeOH, Methyl alcohol

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About This Item

Linear Formula:
CH3OH
CAS Number:
Molecular Weight:
32.04
Beilstein/REAXYS Number:
1098229
MDL number:
Assay:
≥99.75%
Grade:
anhydrous
Technique(s):
tissue processing: suitable
Bp:
64.7 °C
Vapor pressure:
410 mmHg ( 50 °C), 97.68 mmHg ( 20 °C)
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Quality Segment

grade

anhydrous

vapor density

1.1 (vs air), 1.11 (vs air)

vapor pressure

410 mmHg ( 50 °C), 97.68 mmHg ( 20 °C)

description

Various Returnable Container Options

product line

ISOM8

assay

≥99.75%

form

liquid

autoignition temp.

433 °C (811°F), 725 °F

shelf life

60 mo.

expl. lim.

36 %

packaging

Sure/Seal of 1 L, Sure/Seal of 6 × 1 L, Sure/Seal of 12 × 100 mL, Sure/Seal of 4 × 2 L

technique(s)

tissue processing: suitable

impurities

<0.005% water

evapn. residue

<0.0005%

refractive index

n/D 1.3290 (lit.), n20/D 1.329 (lit.)

pH

7 (20  °C, 10 g/L)

bp

64.7 °C

mp

-98 °C, −98 °C (lit.)

transition temp

flash point 13 °C (55°F)

solubility

miscible

density

0.791 g/mL at 20 °C, 0.791 g/mL at 25 °C (lit.)

cation traces

(See Dossier)

suitability

suitable for (histological solvents), suitable for fixing solution

application(s)

diagnostic assay manufacturing
life science and biopharma

SMILES string

CO

InChI

1S/CH4O/c1-2/h2H,1H3

InChI key

OKKJLVBELUTLKV-UHFFFAOYSA-N

General description

Welcome to our ISOM8 line of high-quality products available and able to scale for manufacturing. Within our ISOM8 team, we have expertise and documentation to support ISO 9001 industrial and non-GMP pharma production needs, as defined by our M-Clarity Program.

Our portfolio of ISOM8 products and chemistries is ever evolving to support our valued Sigma-Aldrich® customers′ requirements. Please navigate to our documents section to look at dossiers and other quality documentation for this product, provided with support of our Elevate Quality Program.

Our ISOM8 Methanol is available within the USA with our ReCycler® Solvent System for returnable, reusable, and readily available bulk solvent delivery, to reduce packaging waste and help you achieve your sustainablility goals. To request ISOM8 and other product lines in returnable containers Click Here.

Application

Biomedical Applications
Methanol is widely used in cell fixation processes, preserving cellular structures and morphology for microscopy, immunohistochemistry, and other analytical techniques. Its ability to precipitate proteins and denature nucleic acids makes it an essential tool in biological and biomedical research.
Chemical Synthesis
As a versatile building block in organic synthesis, non-GMP anhydrous methanol serves as a solvent and reagent in the production of pharmaceuticals, agrochemicals, and specialty chemicals, facilitating efficient and effective reactions.
Formulation Development
In the formulation of coatings, adhesives, and sealants, non-GMP anhydrous methanol acts as a solvent, improving the application properties and performance of end products.

Features and Benefits

FEATURES
  • High Purity: Our anhydrous methanol is produced to meet stringent quality standards, ensuring minimal impurities for reliable performance in sensitive applications.
  • Effective Fixative: Serves as a reliable fixative for biological samples, preserving cellular structures for microscopy and analytical techniques.
  • Versatile Applications: Suitable for a wide range of applications including synthesis, extraction, and formulation development.
  • Returnable Containers: Offered in returnable containers, promoting sustainability and responsible resource management.
BENEFITS
  • Reliable Results: The high purity and low water content ensure consistent and reproducible results in versatile applications.
  • Broad Applicability: Suitable for various industries including pharmaceuticals, biotechnology, energy, and manufacturing, making it a valuable addition to your supply chain.
  • Cost Efficiency: Returnable containers can lead to cost savings over time, as customers can reuse them rather than purchasing new packaging for each order.

Packaging

100 mL, 1 L, and 2 L bottles are packaged in Sure/Seal containers.

For bulk amounts in US, we offer returnables through ReCycler® Program.

Legal Information

ISOM8 is a trademark of Sigma-Aldrich Co. LLC
Sure/Seal is a trademark of Sigma-Aldrich Co. LLC
M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany
RECYCLER is a registered trademark of Merck KGaA, Darmstadt, Germany
SIGMA-ALDRICH is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup



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