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Merck
CN

R2253

Rolitetracycline

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C27H33N3O8
CAS Number:
751-97-3
Molecular Weight:
527.57
UNSPSC Code:
41116107
PubChem Substance ID:
329824014
EC Number:
212-031-9
MDL number:
MFCD00056562

Key Documents

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InChI key

HMEYVGGHISAPJR-IAHYZSEUSA-N

InChI

1S/C27H33N3O8/c1-26(37)13-7-6-8-16(31)17(13)21(32)18-14(26)11-15-20(29(2)3)22(33)19(24(35)27(15,38)23(18)34)25(36)28-12-30-9-4-5-10-30/h6-8,14-15,20,31,33-34,37-38H,4-5,9-12H2,1-3H3,(H,28,36)/t14-,15-,20-,26+,27-/m0/s1

SMILES string

[H][C@@]12C[C@@]3([H])C(=C(O)[C@]1(O)C(=O)C(C(=O)NCN4CCCC4)=C(O)[C@H]2N(C)C)C(=O)c5c(O)cccc5[C@@]3(C)O

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

General description

Chemical structure: tetracycline

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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F W Jennings
Research in veterinary science, 43(2), 173-176 (1987-09-01)
The simultaneous administration, to Trypanosoma brucei infected mice, of rolitetracycline or oxytetracycline and diminazene aceturate appeared to have no effect on the initial trypanocidal action of the diminazene aceturate in that trypanosomes were cleared from the circulation. It also had
M Carrozzo et al.
Minerva medica, 78(4), 243-246 (1987-02-28)
A new and easy technique for the fluorimetric evaluation of rolitetracycline calcium complex was studied. The study was carried out in 3 different groups of rats; an increase in power of fluorescence in the rats on a low calcium diet
R K Rencken et al.
The Journal of urology, 143(5), 940-943 (1990-05-01)
Sclerotherapy with 3% sodium tetradecyl sulfate and 3.5% rolitetracycline on an outpatient basis was applied to 55 hydroceles. The over-all cure rate was 96% with an average followup of 13 months. Of the patients 64% were cured after only 1
K Yokoyama
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 61(3), 379-387 (1986-05-01)
The purpose of the present study was to investigate the effect of Tetracyclines (TCs); Minocycline (MINO), Tetracycline (TC), Demethylchlortetracycline (DMTC), Pyrrolidinomethyltetracycline (PMTC), on amino acid transport and incorporation in hepatocytes. By the use of liver cell culture, this study was
M Hirsch et al.
Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 33(5), 721-729 (1990-01-01)
Authors studied the oxygen demand by E. coli suspensions (serotypes 023 and 026) modifying it with various concentration of Rolitetracyclin, and proceeded by comparison of both serotypes. Time dependence of oxygen demand has been determined using the direct Warburg's manometric
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