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Merck
CN

R7635

Ronidazole

analytical standard

Synonym(s):

1-Methyl-2-(carbamoyloxymethyl)-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C6H8N4O4
CAS Number:
Molecular Weight:
200.15
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
231-675-1
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

≥95%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

Cn1c(COC(N)=O)ncc1N(=O)=O

InChI

1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)

InChI key

PQFRTXSWDXZRRS-UHFFFAOYSA-N

General description

Ronidazole is a nitroimidazole compound, commonly used as antiprotozoal and antibacterial agent.

Application

Ronidazole may be used as a reference standard in the determination of the analyte in poultry muscle and eggs using high-performance liquid chromatography with ultraviolet detection and confirmatory analysis by atmospheric pressure chemical ionization-mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Neurotoxicosis in 4 cats receiving ronidazole.
Terri W Rosado et al.
Journal of veterinary internal medicine, 21(2), 328-331 (2007-04-13)
Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry.
Sams JM, et al.
Analyst, 123(1-2), 2545-2549 (1998)
Malcolm Holliday et al.
Journal of feline medicine and surgery, 11(2), 131-134 (2008-09-09)
Faecal samples from 74 cats with chronic large bowel diarrhoea that were living in a rescue colony in Italy, were submitted for assessment of Tritrichomonas foetus by direct microscopy of faecal smears (n=20) and T foetus-specific culture (n=74), with confirmation