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Merck
CN

S0780000

Sodium hyaluronate

BRP, European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Hyaluronic acid sodium salt

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About This Item

CAS Number:
UNSPSC Code:
41116107
NACRES:
NA.24
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Product Name

Sodium hyaluronate, BRP, European Pharmacopoeia (EP) Reference Standard

SMILES string

[Na+].N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(=O)O)O)CO)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3O)CO)O)NC(=O)C)C(=O)O)C(=O)C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChI key

YWIVKILSMZOHHF-QJZPQSOGSA-N

grade

pharmaceutical primary standard

API family

sodium hyaluronate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

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Application

Sodium hyaluronate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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C Thomas Vangsness et al.
The Journal of bone and joint surgery. American volume, 96(2), 90-98 (2014-01-17)
There are limited treatment options for tissue restoration and the prevention of degenerative changes in the knee. Stem cells have been a focus of intense preclinical research into tissue regeneration but limited clinical investigation. In a randomized, double-blind, controlled study
Daniela Elena Costea et al.
Cancer research, 73(13), 3888-3901 (2013-04-20)
Heterogeneity of carcinoma-associated fibroblasts (CAF) has long been recognized, but the functional significance remains poorly understood. Here, we report the distinction of two CAF subtypes in oral squamous cell carcinoma (OSCC) that have differential tumor-promoting capability, one with a transcriptome
Yohei Ono et al.
Biochemical and biophysical research communications, 435(4), 733-739 (2013-05-25)
During osteoarthritis there is a disruption and loss of the extracellular matrix of joint cartilage, composed primarily of type II collagen, aggrecan and hyaluronan. In young patients, autologous chondrocyte implantation can be used to repair cartilage defects. However, for more
Hohyeon Lee et al.
Journal of biomedical nanotechnology, 9(2), 299-302 (2013-05-01)
Cancer recurrence is the main cause of chemotherapeutic treatment failure. The mechanisms driving cancer recurrence may be due to very rare subpopulation cells, cancer stem-like cells (CSCs). Therefore, the early detection and better treatment of cancer stem-like cells are of
Keng Lin Wong et al.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 29(12), 2020-2028 (2013-11-30)
To analyze the results of the use of intra-articular cultured autologous bone marrow-derived mesenchymal stem cell (MSC) injections in conjunction with microfracture and medial opening-wedge high tibial osteotomy (HTO). Fifty-six knees in 56 patients with unicompartmental osteoarthritic knees and genu

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