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S0817

Sodium chloride solution

Name: Sodium chloride solution
Brand: SIAL

0.85%

Synonym(s):

Halite, NaCl, sodium chloride

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About This Item

Linear Formula:

NaCl

CAS Number:

7647-14-5

Molecular Weight:

58.44

UNSPSC Code:

12161700

NACRES:

NA.25

PubChem Substance ID:

24899447

MDL number:

MFCD00003477

Beilstein/REAXYS Number:

3534976

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Quality Level

200

concentration

0.83-0.86% NaCl, 0.85%

density

1.000 g/cm³ at 20 °C

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

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Related Categories

Lab Chemicals

Salts

General description

Sodium chloride is commonly referred to as “salt” and is naturally present as mineral halite. Sodium chloride solution is highly used in chemical production.

Application

Sodium chloride solution has been used in the preparation of neurotoxin 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) stock solution.

Biochem/physiol Actions

Sodium chloride solution is applicable in protein crystallization. It favours better protein-protein interactions.

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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A model of MPTP-induced Parkinson's disease in the goldfish

Weinreb O and Youdim MB

Nature Protocols, 2(11) (2007)

Sodium Chloride

Kirk-Othmer Encyclopedia of Chemical Technology, 1-27 (2000)

Hydrophobic forces between protein molecules in aqueous solutions of concentrated electrolyte.

Curtis RA, et al.

Biophysical Chemistry, 98(3), 249-265 (2002)

Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling.

Justin W Leung et al.

PLoS genetics, 10(3), e1004178-e1004178 (2014-03-08)

Histone ubiquitinations are critical for the activation of the DNA damage response (DDR). In particular, RNF168 and RING1B/BMI1 function in the DDR by ubiquitinating H2A/H2AX on Lys-13/15 and Lys-118/119, respectively. However, it remains to be defined how the ubiquitin pathway

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.

Guus M Bol et al.

EMBO molecular medicine, 7(5), 648-669 (2015-03-31)

Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is overexpressed in many cancer types including lung cancer

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Protocols

Protein Determination Modified Lowry Method

To standardize a procedure for the determination of protein by modified Lowry.

Enzymatic Assay of Aprotinin

Objective: To standardize a procedure for the enzymatic assay of Aprotinin.

Enzymatic Assay of Deoxyribonuclease I (EC 3.1.21.1)

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

抑肽酶酶活测定

抑肽酶是一种牛胰蛋白酶抑制剂。在测定抑肽酶活性时，该测定使用了在405 nm下的连续分光光度法进行测定。

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Global Trade Item Number

SKU	GTIN
S0817-1GA	04061836830861
S0817-5GA	04061838175175

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