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S3674

Succinic acid

Name: Succinic acid
Brand: SIAL

BioXtra, BioRenewable, ≥99.0%

Sustainability features

Synonym(s):

Butanedioic acid

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About This Item

Linear Formula:

HOOCCH₂CH₂COOH

CAS Number:

110-15-6

Molecular Weight:

118.09

UNSPSC Code:

12352106

NACRES:

NA.25

PubChem Substance ID:

24899568

EC Number:

203-740-4

Beilstein/REAXYS Number:

1754069

MDL number:

MFCD00002789

eCl@ss:

32160703

Assay:

≥99.0%

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Properties

Quality Segment

200

product line

BioXtra

assay

≥99.0%

sustainability

Sustainability features

impurities

≤0.01% Insoluble matter

ign. residue

≤0.02%

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

H₂O: 0.5 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.001%, sulfate (SO₄^2-): ≤0.003%

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

greener alternative category

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

Description

General description

This product aligns with one or more of the 12 Principles of Green ChemistryThis product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Succinic acid has been used:

in succinate dehydrogenase mitochondrial assay.
as an internal standard in mass spectroscopy.
as succinate dehydrogenase substrate in oxygraph analysis to measure respiration rates.

Biochem/physiol Actions

Succinic acid is a byproduct of anaerobic fermentation in microbes. It is a dicarboxylic acid and an intermediate in Kreb′s cycle. Polymorphism in succinate dehydrogenase leads to succinate accumulation. High levels of succinate impairs 2-oxoglutarate epigenetic signalling. Succinate levels may modulate tumor progression. Succinate inhibits histone demethylation and may contribute to epigenetic changes. Succinate is crucial for interleukin-1 β (IL-1β) synthesis during inflammation and immune signalling.

Other Notes

Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources

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Pictograms

GHS05

Signal Word

Danger

Hazard Codes

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)