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S8170

Sigma-Aldrich

Sodium nitrate

BioXtra, ≥99.0%

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Synonym(s):
Chile salpeter
Empirical Formula (Hill Notation):
NaNO3
CAS Number:
Molecular Weight:
84.99
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

product line

BioXtra

Quality Level

Assay

≥99.0%

impurities

<0.0005% Phosphorus (P)
<0.1% Insoluble matter

mp

306 °C (dec.) (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.01%
Mg: <0.0005%
NH4+: <0.1%
Pb: <0.001%
Zn: <0.0005%

SMILES string

[Na+].[O-][N+]([O-])=O

InChI

1S/NO3.Na/c2-1(3)4;/q-1;+1

InChI key

VWDWKYIASSYTQR-UHFFFAOYSA-N

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General description

Sodium nitrate is synthesized by treating nitrite with nitric acid. The proportion of nitrite production is higher when synthesized by absorbing waste gases from nitric acid. Supplementation of sodium nitrate may serve to improve acute heart failure (AHF) by modulating the nitric oxide precursor levels.

Application

Sodium nitrate has been used:
  • in combination with beef extract for virus elution from water samples
  • as an external calibrant in nitrate assay to quantify nitrate in cell culture medium
  • as a component of liquid BG11-medium for culturing Synechococcus elongatus PCC 7942
  • to test its protective effects in hepatic ischemia-reperfusion injury

Pictograms

Flame over circleExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Ox. Sol. 3

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 1

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
易制爆化学品

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Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels
Sachdeva R, et al.
Cell Calcium, 78(3), 66-75 (2019)
Re-evaluation of sodium nitrate (E 251) and potassium nitrate (E 252) as food additives
Mortensen A, et al.
EFSA Journal, 15(6), e04787-e04787 (2017)
Quantification of Chlorophyll as a Proxy for Biofilm Formation in the Cyanobacterium Synechococcus elongatus
Sendersky E, et al.
Bio-protocol, 7, e2406-e2406 (2017)
Inorganic nitrate as a treatment for acute heart failure: a protocol for a single center, randomized, double-blind, placebo-controlled pilot and feasibility study
Falls R, et al.
Journal of Translational Medicine, 15(1), 172-172 (2017)
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver
Duranski MR, et al.
The Journal of Clinical Investigation, 115(5), 1232-1240 (2005)

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