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Merck
CN

S9509

(±)-Sulfinpyrazone

analytical standard

Synonym(s):

1,2-Diphenyl-4-(phenylsulfinylethyl)-3,5-pyrazolidinedione, Diphenylpyrazone

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About This Item

Empirical Formula (Hill Notation):
C23H20N2O3S
CAS Number:
57-96-5
Molecular Weight:
404.48
NACRES:
NA.24
PubChem Substance ID:
329824625
UNSPSC Code:
41116107
EC Number:
200-357-4
MDL number:
MFCD00057279

Key Documents

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Product Name

(±)-Sulfinpyrazone, analytical standard

InChI key

MBGGBVCUIVRRBF-UHFFFAOYSA-N

InChI

1S/C23H20N2O3S/c26-22-21(16-17-29(28)20-14-8-3-9-15-20)23(27)25(19-12-6-2-7-13-19)24(22)18-10-4-1-5-11-18/h1-15,21H,16-17H2

SMILES string

O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4

grade

analytical standard

assay

≥99%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Gene Information

human ... SLC22A12(116085)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Sulfinpyrazone is a 1,3-dicarbonyl uricosuric drug used in the treatment of hyperuricemia associated with gout.

Hazard Classifications

Acute Tox. 4 Oral

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6270
BCCH7074
BCCF8696
BCCC7636
BCBX5482

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High-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites
Holcapek M, et al.
Analytical and Bioanalytical Chemistry, 391(1), 59-78 (2008)
Screening of xanthine oxidase inhibitor from selected edible plants and hypouricemic effect of Rhizoma Alpiniae Officinarum extract on hyperuricemic rats
Lin L, et al.
Journal of functional foods, 50(1), 26-36 (2018)
Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9 (UGT1A9)
Kerdpin O, et al.
Drug Metabolism and Disposition, 50(1), 26-36 (2006)
Leslie R Harrold et al.
Arthritis research & therapy, 11(2), R46-R46 (2009-03-31)
Adherence to urate-lowering drugs (ULDs) has not been well evaluated among those with gout. Our aim was to assess the level and determinants of non-adherence with ULDs prescribed for gout. We identified persons using two integrated delivery systems aged 18
Tetsuya Oguri et al.
Molecular cancer therapeutics, 7(5), 1150-1155 (2008-05-01)
We used the paclitaxel-resistant human small cell lung cancer subline PC-6/TAX1-1, selected from PC-6 cells by paclitaxel, to test whether MRP7/ABCC10 (ABCC10) confers paclitaxel resistance. We found that gene expression of both ABCB1/MDR1 (ABCB1) and ABCC10 was higher in PC-6/TAX1-1
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