SMB01360
1-MethylpseudoUridine
≥98% (HPLC)
Synonym(s):
1-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, N1-Methylpseudouridine
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About This Item
Empirical Formula (Hill Notation):
C10H14N2O6
CAS Number:
Molecular Weight:
258.23
MDL number:
UNSPSC Code:
41106305
NACRES:
NA.21
Quality Level
Assay
≥98% (HPLC)
form
solid
storage temp.
2-8°C
SMILES string
[nH]1[c]([n](cc([c]1=O)[C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)C)=O
InChI
1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1
InChI key
UVBYMVOUBXYSFV-XUTVFYLZSA-N
General description
A key aspect of COVID-19 mRNA vaccines is the use of the modified nucleobase Methylpseudouridine to increase their effectiveness. The modified nucleobase helps cloak mRNA vaccines from the immune system, limiting their undesired immune stimulation, and in certain circumstances may also enhance the synthesis of antigens.
Application
Vaccine development
Other Notes
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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