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Merck
CN

SMB01360

1-MethylpseudoUridine

≥98% (HPLC)

Synonym(s):

1-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, N1-Methylpseudouridine

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About This Item

Empirical Formula (Hill Notation):
C10H14N2O6
CAS Number:
Molecular Weight:
258.23
UNSPSC Code:
41106305
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage temp.:
2-8°C
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Quality Level

assay

≥98% (HPLC)

form

solid

storage temp.

2-8°C

SMILES string

[nH]1[c]([n](cc([c]1=O)[C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)C)=O

InChI

1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1

InChI key

UVBYMVOUBXYSFV-XUTVFYLZSA-N

General description

A key aspect of COVID-19 mRNA vaccines is the use of the modified nucleobase Methylpseudouridine to increase their effectiveness. The modified nucleobase helps cloak mRNA vaccines from the immune system, limiting their undesired immune stimulation, and in certain circumstances may also enhance the synthesis of antigens.

Application

Vaccine development

Other Notes

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Global Trade Item Number

SKUGTIN
SMB01360-250MG04065267166353
SMB01360-50MG04065267166360