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Sigma-Aldrich

ECO Brij® S10

greener alternative

average Mn ~711

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Synonym(s):
Brij® S10, Polyethylene glycol octadecyl ether, Polyoxyethylene (10) stearyl ether
Linear Formula:
C18H37(OCH2CH2)nOH, n~10
CAS Number:
9005-00-9
MDL number:
MFCD00074177

description

non-ionic

Quality Level

200

form

solid

mol wt

average Mn ~711

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

mp

37-39 °C (lit.)

density

0.964 g/mL at 25 °C (lit.)

HLB

12.4

greener alternative category

Aligned,

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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General description

ECO Brij® S10 is an ethoxylated natural fatty alcohol, a nonionic bio-based surfactant that belongs to the class of polyoxyethylene ethers. This naturally derived detergent offers a number of functional benefits including detergency, wetting and dispersing making it suitable for a range of applications in biochemical and biological research.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Features and Benefits

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Brij is a registered trademark of Croda International PLC
ECO BRIJ is a registered trademark of Croda Inc.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 161(1), 142-149 (2012-04-17)
Here we report the development of an enhanced thermosensitive formulation composed of DPPC and Brij78, loaded with doxorubicin (DOX) using a Cu²⁺ gradient and post-inserted with an additional amount of Brij78. This optimal formulation (HaT-II: Hyperthermia-activated cytoToxic) displayed significantly improved
Jigna D Patel et al.
Pharmaceutical research, 24(2), 343-352 (2006-12-21)
The purpose of these studies was to prepare nanoparticles (NPs) with a small amount of surface-chelated nickel for obtaining enhanced binding of histidine-tagged (his-tag) proteins compared to non-histidine-tagged protein binding to charged nanoparticles. NPs were prepared from oil-in-water microemulsion precursors
Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 152(2), 303-309 (2011-02-23)
We have developed a novel and simplified thermosensitive liposomal formulation (HaT: Hyperthermia-activated cytoToxic) composed of DPPC lipid and Brij78 (96:4, molar ratio). The HaT nanoparticles were loaded with doxorubicin (DOX) with >95% efficiency when a pH gradient method and a
Joanna M Koziara et al.
Journal of controlled release : official journal of the Controlled Release Society, 99(2), 259-269 (2004-09-24)
Despite the advances in tumor therapy, patients with primary brain tumors and brain metastases have a very poor prognosis. Low responses to chemotherapy are mainly attributed to impermeability of the blood-brain barrier to cytotoxic agents. Paclitaxel has been shown to
J Q Zhang et al.
Drug delivery, 14(6), 381-387 (2007-08-19)
The study describes the development of stealth solid lipid nanoparticles (SLNs) as colloidal carriers for silibinin, a drug with very low solubility. Stealth SLNs were constituted mainly of bioacceptable and biodegradable lipids, such as stearic acid and surfactant Brij 78
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