SYNPLE-A012
Reagent-cartridge Amide formation (for amine salts)
Synple
Synonym(s):
Synple 2
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About This Item
reaction suitability
reaction type: Amidations
SMILES string
[s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
InChI key
HVPZHRHEHKZOOJ-TYBLODHISA-N
General description
Reagent-cartridge Amide formation (for amine salts) is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the amide coupling of carboxylic acids and amines. The cartridge contains all necessary reagents for amide coupling and purification.
Scale: up to 0.5 mmol
Compatible substrates: carboxylic acids, primary and secondary alkyl amine salts
Cartridge contents:
• Supported carbodiimide and Oxyma Pure (coupling reagents)
• SCX2 (for purification)
• Supported carbonate (acid scavenger)
Learn more about the Synple automated synthesis platform.
Features and Benefits of Synple Platform
• Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
• Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety – all chemicals are contained in the system, minimizing the user’s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system – simple installation
• Reaction temperatures from 25 °C – 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol
Scale: up to 0.5 mmol
Compatible substrates: carboxylic acids, primary and secondary alkyl amine salts
Cartridge contents:
• Supported carbodiimide and Oxyma Pure (coupling reagents)
• SCX2 (for purification)
• Supported carbonate (acid scavenger)
Learn more about the Synple automated synthesis platform.
Features and Benefits of Synple Platform
• Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
• Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety – all chemicals are contained in the system, minimizing the user’s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system – simple installation
• Reaction temperatures from 25 °C – 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol
Legal Information
Product of Synple Chem AG
Storage Class
11 - Combustible Solids
WGK
WGK 3
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