SYNPLE-H011
Reagent-cartridge Morpholine-2-spiro-(4-Pip)
Synple
Synonym(s):
Synple 2
Quality Level
parameter
up to 0.5 mmol scale
SMILES string
[s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
InChI key
HVPZHRHEHKZOOJ-TYBLODHISA-N
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General description
Reagent-cartridge Morpholine-2-spiro-(4-Pip) is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the synthesis of a morpholine-piperidine spirocycle from an aldehyde through the use of a SnAP reagent. The cartridge contains all necessary reagents for transforming the chosen aldehyde into a morpholine-piperidine spirocycle.
Scale: up to 0.5 mmol
Heterocycle: Morpholine-piperdine spirocycle
Compatible substrates: aldehyde
Cartridge contents:
Related Cartridges:
Learn more about the Synple automated synthesis platform.
Features and Benefits of Synple Platform
Scale: up to 0.5 mmol
Heterocycle: Morpholine-piperdine spirocycle
Compatible substrates: aldehyde
Cartridge contents:
- Immobilized SnAP reagent
- Cu catalyst (Cu(OTF)2 and 2,6-lutidinium triflate)
- SCX (for purification)
- Silica (for purification)
Related Cartridges:
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- SYNPLE-H004Reagent-cartridge 2-Methylmorpholine
- SYNPLE-H005Reagent-cartridge Piperazine
- SYNPLE-H006Reagent-cartridge Diazepane
- SYNPLE-H007Reagent-cartridge 3-Methylmorpholine
- SYNPLE-H010Reagent-cartridge Morpholine-2-spiro-(2-Pyr)
- SYNPLE-H090Reagent-cartridge 9-OMe-Benzoxazepane
- SYNPLE-H091Reagent-cartridge 7-Br-9-OMe-Benzoxazepane
Learn more about the Synple automated synthesis platform.
Features and Benefits of Synple Platform
- Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
- Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
- Safety - all chemicals are contained in the system, minimizing the user′s exposure
- Set-up reaction in less than 5 minutes
- Small footprint
- Plug & Play system - simple installation
- Reaction temperatures from 25 °C - 80 °C
- Cartridges available for many different reactions
- Prefilled with all required reagents
- RFID chip containing optimized reaction protocol
Other Notes
An integrated console for capsule-based, automated organic synthesis
For more information on heterocycle formation using SnAP reagents, visit here: SnAP Technology Spotlight
For more information on heterocycle formation using SnAP reagents, visit here: SnAP Technology Spotlight
Legal Information
Product of Synple Chem AG
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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