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Merck
CN

SYNPLE-R001

Reagent-cartridge Reductive Amination

Synple

Synonym(s):

Synple 2

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.22
MDL number:
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SMILES string

[s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C

InChI key

HVPZHRHEHKZOOJ-TYBLODHISA-N

Quality Level

reaction suitability

reaction type: Reductive Aminations

parameter

up to 0.5 mmol scale

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General description

Reagent-cartridge Reductive Amination is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the reductive amination of aldehydes and ketones. The cartridge contains all necessary reagents for condensation, reduction, and purification.

Scale: up to 0.5 mmol
Compatible substrates: aldehydes, ketones, primary amines, secondary amines

Cartridge contents:
  • Reducing agent (supported cyanoborohydride)
  • Proton source (Phenylacetic acid)
  • SCX (for purification)
  • Supported benzaldehyde (amine scavenger)

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform
  • Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
  • Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
  • Safety - all chemicals are contained in the system, minimizing the user′s exposure
  • Set-up reaction in less than 5 minutes
  • Small footprint
  • Plug & Play system - simple installation
  • Reaction temperatures from 25 °C - 80 °C
  • Cartridges available for many different reactions
  • Prefilled with all required reagents
  • RFID chip containing optimized reaction protocol

Legal Information

Product of Synple Chem AG

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

易制毒化学品(2类)
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Articles

Discover Synple 2, an automated organic chemical synthesis system that allows researchers to have their products generated for them while reducing both human error and manual labor.

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