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Merck
CN

T6159

Trimebutine

analytical standard

Synonym(s):

3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester

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About This Item

Empirical Formula (Hill Notation):
C22H29NO5
CAS Number:
39133-31-8
Molecular Weight:
387.47
NACRES:
NA.24
PubChem Substance ID:
329826841
UNSPSC Code:
41116107
EC Number:
254-309-2
MDL number:
MFCD00133873

Key Documents

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InChI key

LORDFXWUHHSAQU-UHFFFAOYSA-N

InChI

1S/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3

SMILES string

CCC(COC(=O)c1cc(OC)c(OC)c(OC)c1)(N(C)C)c2ccccc2

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

Quality Level

200

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Imke Masuy et al.
Alimentary pharmacology & therapeutics, 49(9), 1134-1172 (2019-03-30)
Functional dyspepsia, consisting of epigastric pain syndrome and postprandial distress syndrome, is a prevalent functional gastrointestinal disorder. To date, only limited treatment options are available and conflicting results in terms of efficacy have been reported. Consequently, nonpharmacological treatment options are
A V Krymchantowski et al.
Cephalalgia : an international journal of headache, 26(7), 871-874 (2006-06-17)
Gastroparesis frequently happens during migraine attacks, postponing the onset of action of orally administered drugs. Furthermore, triptans seem to work better in the earlier phases of the migraine attacks. Therefore, associating a gastrokinetic drug with a triptan may translate into
O Bekem et al.
Acta gastro-enterologica Belgica, 68(4), 416-418 (2006-01-26)
Of the feeding disorders in children, poor appetite is probably one of the most common complaints notified by parents. Since gastric motility disorders may be the cause of this symptom, the aim of our study was to investigate the effect
Kwan Hyung Cho et al.
International journal of pharmaceutics, 400(1-2), 145-152 (2010-09-10)
To develop a novel combination tablet which contained 100 mg trimebutine maleate and 5 mg mosapride citrate (TMCT) for the treatment of functional dyspepsia, the wet granulation method was used to prepare TMCTs with various amounts of diluents and stabilizers.
Toru Hiyama et al.
Journal of gastroenterology and hepatology, 22(10), 1566-1570 (2007-09-12)
Functional dyspepsia (FD) is often treated with serotonin agonists; however, the efficacy of such agents has recently been questioned. The aim of this study was to perform a meta-analysis of randomized controlled trials (RCTs) comparing serotonin agonists with other types
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