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T7511

Supelco

Tripelennamine hydrochloride

analytical standard

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Synonym(s):
2-(Benzyl[2-dimethylaminoethyl]amino)pyridine, N-Benzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine hydrochloride, Pyribenzamine hydrochloride
Empirical Formula (Hill Notation):
C16H21N3 · HCl
CAS Number:
154-69-8
Molecular Weight:
291.82
EC Number:
205-833-5
MDL number:
MFCD00012815
PubChem Substance ID:
329826868
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.Cl

InChI

1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H

InChI key

FSSICIQKZGUEAE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

Tripelennamine hydrochloride is an antihistamine drug, which is used in the treatment of bronchitis, asthma and bronchoconstriction.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tripelennamine hydrochloride may be used as a reference standard in the determination of tripelennamine hydrochloride in samples of animal feed by gas chromatography (GC) method, wastewater and urine using high performance liquid chromatography (HPLC) method employing fluorescence detector.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 - H315 - H319 - H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Trace determination of the antihistamines tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate in admixture in animal feed, human urine, and wastewater by high-pressure liquid chromatography and use of a fluorescence detector.
Thompson TH, et al.
Talanta, 30(4), 251-260 (1983)
T Sato et al.
Japanese journal of pharmacology, 71(1), 81-84 (1996-05-01)
Effects of histamine H1-receptor antagonists on L-dopa-induced behavioral excitement were examined in mice to confirm behaviorally the inhibition of dopamine uptake by these compounds. L-Dopa (100-300 mg/kg, s.c.) combined with pargyline hydrochloride (80 mg/kg, i.p.) caused a dose-dependent behavioral excitement.
Ulrich Schlecht et al.
PloS one, 7(8), e42853-e42853 (2012-08-21)
Meiosis is a highly regulated developmental process that occurs in all eukaryotes that engage in sexual reproduction. Previous epidemiological work shows that male and female infertility is rising and environmental factors, including pollutants such as organic solvents, are thought to
Shilpa P Sakhalkar et al.
International immunopharmacology, 5(7-8), 1299-1309 (2005-05-26)
Signal transducer and activator of transcription-1 (STAT1) is a latent signal transducer protein which, on phosphorylation, is translocated from the cytoplasm to the nucleus and is subsequently activated. This study was designed to determine the involvement of histamine receptors in
C E Johanson et al.
Psychopharmacology, 126(2), 140-146 (1996-07-01)
Twenty volunteers were trained to discriminate between 75 mg tripelennamine (TP) and placebo. During the first four sessions, the drugs were identified prior to ingestion by letter code. During the next six sessions, the procedure was the same except the
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