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T8656

Thiourea

Name: Thiourea
Brand: SIAL

ACS reagent grade, ≥99.0%

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:

NH₂CSNH₂

CAS Number:

62-56-6

Molecular Weight:

76.12

NACRES:

NA.21

PubChem Substance ID:

24900549

UNSPSC Code:

12352100

EC Number:

200-543-5

MDL number:

MFCD00008067

Beilstein/REAXYS Number:

605327

Assay:

≥99.0%

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Product Name

Thiourea, ACS reagent, ≥99.0%

grade

ACS reagent

Quality Level

200

assay

≥99.0%

ign. residue

≤0.1% (as SO₄)

loss

≤0.5% loss on drying, 105°C, 2h

mp

170-176 °C (lit.), 174-177 °C

solubility

H₂O: passes test

functional group

amine, thiourea

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Gene Information

mouse ... Ephx2(13850)

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General description

Thiourea is an analogue of urea containing sulphur.

Application

Thiourea has been used:

as a component of lysis buffer for liver tissue homogenization
in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay
in rehydration buffer for protein extraction

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H302,H351,H361fd,H411

pcodes

P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches

Gupta YR, et al.

Aquaculture and Fisheries, 1(2), 15-23 (2016)

Investigation of protein-tyrosine phosphatases by in-gel assays.

Markova B, et al.

Methods, 35(1), 22-27 (2005)

Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium

Osunlaja AA

International Journal of ChemTech Research, 4(2), 609-617 (2012)

Development of chiral thiourea catalysts and its application to asymmetric catalytic reactions.

Yoshiji Takemoto

Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)

We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that

Thiourea derived Tröger's bases as molecular cleft receptors and colorimetric sensors for anions.

Elaine M Boyle et al.

The Journal of organic chemistry, 78(17), 8312-8319 (2013-08-01)

Thiourea-functionalized Tröger's base receptors 1 and 2 have been synthesized and evaluated as novel for the recognition of anions. Receptor 2 gave rise to significant changes in the absorption spectrum upon titration with AcO(-) and H2PO4(-) and acted as a

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Global Trade Item Number

SKU	GTIN
T8656-100G	04061837379499
T8656-500G	04061837379505
T8656-50G	04061837379512

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