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U5128

Urea

Name: Urea
Brand: SIAL

ACS reagent grade, ≤0.001% (Heavy Metals by ICP-OES, metals basis), 99.0-100.5%, solid

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:

NH₂CONH₂

CAS Number:

57-13-6

Molecular Weight:

60.06

NACRES:

NA.21

PubChem Substance ID:

24900652

UNSPSC Code:

12352100

EC Number:

200-315-5

MDL number:

MFCD00008022

Beilstein/REAXYS Number:

635724

Assay:

≤0.001% (Heavy Metals by ICP-OES, metals basis), 99.0-100.5%

Form:

solid

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Properties

Product Name

Urea, ACS reagent, 99.0-100.5%

grade

ACS reagent

Quality Level

200

assay

≤0.001% (Heavy Metals by ICP-OES, metals basis), 99.0-100.5%

form

solid

impurities

≤0.01% Insoluble matter

ign. residue

≤0.01%

mp

132-135 °C (lit.)

solubility

H₂O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl^-): ≤5 ppm, sulfate (SO₄^2-): ≤0.001%

cation traces

Fe: ≤0.001%

functional group

amine

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

Description

General description

Urea is a colourless organic compound, without any odour. It is easily soluble in water.

Application

Urea has been used:

to adjust the urea nitrogen concentration to a preferred range in blood reservoir for evaluating the dialyzer urea clearance
to prepare standards to measure urea synthesis
to prepare standards for blood urea nitrogen assay

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Biochem/physiol Actions

Urea participates in the metabolism of nitrogenous substances. It serves as a nitrogen source, when used in fertilizers. Urea is used in manufacturing chemical compounds. It is widely used in the agricultural industry as a fertilizer as well as an animal feed additive, which is used as a nitrogen supplement in animal husbandry. Urea has adverse effects on seed germination, seedling growth and early plant growth in soil.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

The Carbon Enigma: Material Fundamentals and Retention Properties for Porous Graphitic Carbon (PGC) Stationary Phases

A shortened review of fundamentals of Porous Graphitic Carbon (PGC) materials. What they are and how do they work as a stationary phase material in HPLC?.

Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates

Leypoldt JK, et al.

Kidney International, 51(6), 2013-2017 (1997)

CHAPTER 16 - METHODS OF FEEDING UREA TO LIVESTOCK

Urea As a Protein Supplement, 321-327 (1967)

Hepatic targeting and biodistribution of human fetal liver stem/progenitor cells and adult hepatocytes in mice

Cheng K, et al.

Hepatology, 50(4), 1194-1203 (2009)

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Global Trade Item Number

SKU	GTIN
U5128-100G	04061835559886
U5128-1KG	04061835559893
U5128-5G	04061837409738
U5128-500G	04061835559909
U5128-5KG	04061835559916