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Merck
CN

Y0000063

Heptaminol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-Amino-2-methyl-2-heptanol hydrochloride, Heptaminol hydrochloride

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About This Item

Linear Formula:
CH3CH(NH2)(CH2)3C(OH)(CH3)2 · HCl
CAS Number:
Molecular Weight:
181.70
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3673011
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Product Name

Heptaminol hydrochloride, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H

SMILES string

Cl.CC(N)CCCC(C)(C)O

InChI key

JZNBMCOSOXIZJB-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

heptaminol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Heptaminol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Emmanouil Lyris et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 827(2), 199-204 (2005-10-26)
A study of the metabolism of isometheptene, an antispasmodic drug, in man and comparison with heptaminol metabolism, is presented in this paper. Isometheptene and two metabolites were detected in human urine after oral administration of a tablet containing isometheptene mucate.
B Fontas et al.
Canadian journal of physiology and pharmacology, 68(7), 791-799 (1990-07-01)
Electrophysiological and transport effects induced by heptaminol hydrochloride were studied in frog epithelium. This tissue, which can easily be maintained in vitro, is a valuable model for studying sodium active transport with hormone-dependent characteristics that reproduce mammalian nephron behavior (notably
B Allard et al.
British journal of pharmacology, 104(3), 714-718 (1991-11-01)
1. Heptaminol stopped or delayed the progressive decline in tension which characterizes the phenomenon of fatigue in frog isolated twitch muscle fibre. 2. Heptaminol had no action on the sodium, potassium and calcium voltage-dependent ionic conductances. 3. The hypothesis of
F Seguin et al.
Magnetic resonance in medicine, 14(2), 396-400 (1990-05-01)
Moving average can be used to improve the signal-to-noise ratio of NMR kinetic studies. The method was tested on simulated spectra with time-dependent intensities or peak positions. It was then applied to a series of in vivo spectra, showing the
Kanit Sumboonnanonda et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 87(2), 137-142 (2004-04-06)
The aim of this study was to assess the clinical efficacy, compliance and safety of Ginko biloba--Troxerutin-Heptaminol Hce in the treatment of patients with acute hemorrhoidal attacks in Thailand. In a prospective clinical study on hospital outpatients, the authors studied

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