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Merck
CN

Y0000199

Ciprofloxacin hydrochloride for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Ciprofloxacin hydrochloride monohydrate

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About This Item

Empirical Formula (Hill Notation):
C17H18FN3O3 · HCl · H2O
CAS Number:
86393-32-0
Molecular Weight:
385.82
NACRES:
NA.24
PubChem Substance ID:
329830881
UNSPSC Code:
41116107
MDL number:
MFCD00242856

Key Documents

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Product Name

Ciprofloxacin hydrochloride for peak identification, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2

SMILES string

O.Cl.OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O

InChI key

ARPUHYJMCVWYCZ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

ciprofloxacin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Ciprofloxacin hydrochloride for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Katie J Aldred et al.
Nucleic acids research, 41(8), 4628-4639 (2013-03-06)
Although quinolones are the most commonly prescribed antibacterials, their use is threatened by an increasing prevalence of resistance. The most common causes of quinolone resistance are mutations of a specific serine or acidic residue in the A subunit of gyrase
David J Serisier et al.
Thorax, 68(9), 812-817 (2013-05-18)
The delivery of antipseudomonal antibiotics by inhalation to Pseudomonas aeruginosa-infected subjects with non-cystic fibrosis (CF) bronchiectasis is a logical extension of treatment strategies successfully developed in CF bronchiectasis. Dual release ciprofloxacin for inhalation (DRCFI) contains liposomal ciprofloxacin, formulated to optimise
Roles of the superoxide dismutase SodB and the catalase KatA in the antibiotic resistance of Campylobacter jejuni.
Sunyoung Hwang et al.
The Journal of antibiotics, 66(6), 351-353 (2013-04-04)
Nancy E Caceres et al.
PloS one, 8(3), e58285-e58285 (2013-03-19)
Overexpression of multidrug transporters is a well-established mechanism of resistance to chemotherapy, but other changes may be co-selected upon exposure to drugs that contribute to resistance. Using a model of J774 macrophages made resistant to the fluoroquinolone antibiotic ciprofloxacin and
Patrik Ellström et al.
International journal of medical microbiology : IJMM, 303(3), 134-139 (2013-03-27)
Recent studies have indicated a role of the lipooligosaccharide (LOS) of Campylobacter jejuni in the severe neurological Guillain Barré syndrome, as well as in development of more severe symptoms of acute enteritis. We evaluated the role of the LOS locus
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