Product Name
Almagate, European Pharmacopoeia (EP) Reference Standard
SMILES string
[Al](O)(O)O.[Mg+2].[Mg+2].[Mg+2].[O-]C(=O)[O-].[O-H].[O-H].[O-H].[O-H].O.O
InChI
1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9
InChI key
MTEOMEWVDVPTNN-UHFFFAOYSA-E
grade
pharmaceutical primary standard
API family
almagate
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Application
Almagate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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E Rey et al.
Alimentary pharmacology & therapeutics, 20(6), 683-688 (2004-09-09)
To compare the effect of effervescent ranitidine, almagate (magnesium carbonate-aluminium hydroxide) and placebo on gastric pH, in fasting and postprandial conditions. Twelve healthy volunteers underwent a gastro-oesophageal pH monitoring on three different occasions after the administration of each of the
Can aluminium-containing antacid produce dementia?
K Jobst et al.
Nephron, 71(4), 473-473 (1995-01-01)
J V Esplugues et al.
The Journal of pharmacy and pharmacology, 47(2), 128-130 (1995-02-01)
The study was designed to analyse the protective effects of almagate on a model of gastric injury, ethanol-induced mucosal damage, in which acid plays little, if any, role. Pretreatment with almagate dose-dependently reduced the level of gastric damage induced by
C L Peterson et al.
Pharmaceutical research, 10(7), 998-1004 (1993-07-01)
The composition and antacid properties of 10 samples of crystalline antacids containing both aluminum and magnesium were determined. The composition was found to vary significantly, even within the same type of antacid. For example, three of four hydrotalcite samples exhibit
E Nagy et al.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 32(3), 119-121 (1994-03-01)
The kinetics of aluminium absorption were determined in patients with duodenal ulcer and in 2 normal males after taking the antacid Tisacid (Biogal, Hungary). A peak serum aluminium of 54.5 micrograms/l was reached at 30 min, returning to the initial
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