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About This Item
Empirical Formula (Hill Notation):
C17H9Cl3N4O2
CAS Number:
Molecular Weight:
407.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI key
ZSZFUDFOPOMEET-UHFFFAOYSA-N
SMILES string
Clc1ccc(cc1)C(C#N)c2c(Cl)cc(cc2Cl)N3N=CC(=O)NC3=O
InChI
1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)
grade
pharmaceutical primary standard
API family
diclazuril
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Diclazuril for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2
target_organs
Lungs,Liver,lymph node
Storage Class
11 - Combustible Solids
wgk
WGK 2
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Bian-hua Zhou et al.
Parasitology research, 111(4), 1447-1455 (2012-07-04)
The receptor for activated C kinase (RACK) cDNA of second-generation merozoites of Eimeria tenella was cloned using reverse transcriptase polymerase chain reaction and rapid amplification of cDNA ends, compared with other species, and then successfully expressed using the pET-28a vector
Antonio Ruiz et al.
Parasitology research, 110(6), 2131-2136 (2011-12-24)
Coccidiosis is probably the main parasitic disease affecting goat kids around the weaning period, leading to high economic losses in goat production due to deaths and delayed growth rates of infected animals. A total of 101 kids of 2-4 weeks
Bianhua Zhou et al.
Veterinary parasitology, 168(3-4), 217-222 (2009-12-17)
Diclazuril, a benzeneacetonitrile anticoccidial agent, has potent activity against various stages of Eimeria tenella (E. tenella). To study the effects of diclazuril on E. tenella merozoites, purified second-generation merozoites were obtained from infected chicken caecal tissue at 120h after inoculation
H W Peek et al.
Avian diseases, 50(3), 434-439 (2006-10-17)
Twenty European Eimeria spp. field isolates were subjected to an anticoccidial sensitivity test (AST). The anticoccidial drugs tested were diclazuril (Clinacox) and monensin (Elancoban). The assay was performed in a battery cage trial. Infected medicated birds were compared with an
Xiaojiong Shen et al.
Veterinary parasitology, 185(2-4), 290-295 (2011-11-15)
Eimeria tenella (E. tenella) is one of the most virulent pathogens of coccidiosis. In apicomplexan parasites, Hsp90 (Heat shock protein 90) is essential for the invasion and survival in host cells. In this study, the effect of diclazuril, an effective
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