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Y0000610

Cladribine impurity C

Name: Cladribine impurity C
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Chloroadenine, 2-Chloro-6-aminopurine

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About This Item

Empirical Formula (Hill Notation):

C₅H₄ClN₅

CAS Number:

1839-18-5

Molecular Weight:

169.57

NACRES:

NA.24

PubChem Substance ID:

329831049

UNSPSC Code:

41116107

MDL number:

MFCD00037925

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Properties

grade

pharmaceutical primary standard

API family

cladribine

manufacturer/tradename

EDQM

mp

384-389 °C

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

SMILES string

Nc1nc(Cl)nc2nc[nH]c12

InChI

1S/C5H4ClN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)

InChI key

HBJGQJWNMZDFKL-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cladribine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 + P330 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides.

Kinga Banach et al.

Nucleosides, nucleotides & nucleic acids, 24(5-7), 465-469 (2005-10-27)

A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an

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Peng Li et al.

Biochemical pharmacology, 79(7), 1015-1024 (2009-11-10)

Since the heterologous tolerance that develops after chronic morphine administration has been proposed to be an adaptive process, it follows that the time course of the change in the cellular components should coincide with the time course of the altered

Laura Willems et al.

Journal of molecular and cellular cardiology, 38(2), 245-256 (2005-02-09)

Aging is associated with reduced tolerance to ischemic insult, and genesis of this intolerant phenotype is poorly understood. We characterized effects of aging and gender on cardiovascular function and cell damage during 20 min ischemia and 60 min reperfusion in

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Global Trade Item Number

SKU	GTIN
Y0000610	04061835123568