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Y0000616

Tropisetron hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Tropisetron monohydrochloride, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride, 3-Tropanylindole-3-carboxylate monohydrochloride, ICS-205,930, Navoban

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About This Item

Empirical Formula (Hill Notation):
C17H20N2O2 · HCl
CAS Number:
105826-92-4
Molecular Weight:
320.81
NACRES:
NA.24
PubChem Substance ID:
329831051
UNSPSC Code:
41116107
MDL number:
MFCD00210221
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grade

pharmaceutical primary standard

API family

tropisetron

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CN1C2CCC1CC(C2)OC(=O)c3c[nH]c4ccccc34

InChI

1S/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H

InChI key

XIEGSJAEZIGKSA-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tropisetron hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Selective 5-HT3 serotonin receptor antagonist.
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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