Y0000836
Nifuroxazide
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone
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About This Item
Empirical Formula (Hill Notation):
C12H9N3O5
CAS Number:
Molecular Weight:
275.22
Beilstein:
4264976
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
nifuroxazide
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
Oc1ccc(cc1)C(=O)N\N=C\c2ccc(o2)[N+]([O-])=O
InChI
1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+
InChI key
YCWSUKQGVSGXJO-NTUHNPAUSA-N
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Nifuroxazide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Determination of nifuroxazide in biological fluid by automated high-performance liquid chromatography with large-volume injection.
Guinebault R P, et al.
Journal of Chromatography A, 204, 329-333 (1981)
Maurice Hofnung et al.
Research in microbiology, 153(7), 427-434 (2002-10-31)
Two nitrofurans present broad-spectrum antimicrobial properties and some of them are used in human and veterinary medicine. Most of these molecules are mutagens and some of them were reported as carcinogens. Due to its extreme mutagenic potency in bacteria, the
S R Walker et al.
Oncogene, 34(9), 1073-1082 (2014-03-26)
Inappropriate expression or activation of transcription factors can drive patterns of gene expression, leading to the malignant behavior of breast cancer cells. We have found that the transcriptional repressor BCL6 is highly expressed in breast cancer cell lines, and its
A Kaufmann et al.
Analytica chimica acta, 862, 41-52 (2015-02-16)
An ultra-high performance liquid chromatography based method, coupled to high resolution mass spectrometry (UHPLC-HRMS), was developed to permit the detection and quantification of various nitrofuran and chloramphenicol residues in a number of animal based food products. This method is based
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