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Y0001751

Mangiferin

Name: Mangiferin
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

1,3,6,7-Tetrahydroxyxanthone C₂-β-D-glucoside, Chinomin, Chinonin, Shamimin

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₁₈O₁₁

CAS Number:

4773-96-0

Molecular Weight:

422.34

NACRES:

NA.24

PubChem Substance ID:

329831551

UNSPSC Code:

12352205

MDL number:

MFCD00075656

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Properties

grade

pharmaceutical primary standard

API family

mangiferin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

InChI key

AEDDIBAIWPIIBD-ZJKJAXBQSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mangiferin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS06

signalword

Danger

hcodes

H300

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Mangiferin suppresses human metastatic osteosarcoma cell growth by down-regulating the expression of metalloproteinases-1/2 and parathyroid hormone receptor 1.

Jifeng Wen et al.

AMB Express, 10(1), 13-13 (2020-01-20)

The study evaluates the protective effect of mangiferin on osteosarcoma cell proliferation and metastasis. Saos-2 and U2OS cells were treated with mangiferin (25, 50, 75 and 100 µM) for 72 h. Mangiferin reduced the cell viability, invasion, and cell adhesion and migration

Global Trade Item Number

SKU	GTIN
Y0001751	04061833838112