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03129

Sigma-Aldrich

Sodium iodide

puriss., meets analytical specification of Ph. Eur., BP, USP, 99-100.5% (calc. to the dried substance)

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Linear Formula:
NaI
CAS Number:
7681-82-5
Molecular Weight:
149.89
EC Number:
231-679-3
MDL number:
MFCD00003532
PubChem Substance ID:
329747563
NACRES:
NB.22

vapor density

>1 (vs air)

Quality Level

200

grade

puriss.

Assay

99-100.5% (calc. to the dried substance)

form

crystalline

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

alkalic reac. Impurities, complies
 barium and thiosulfate, complies
 organic volatile impurities, complies (GC)
 residual solvents, in accordance
≤0.0005% heavy metals (as Pb)
≤0.003% total nitrogen (N)
≤0.005% thiosulfate (S2O3)
≤0.02% free alkali (as NaOH)
≤2% water (Karl Fischer)

loss

≤2% loss on drying, 105 °C

pH

6-9 (20 °C, 50 g/L)

mp

661 °C (lit.)

anion traces

bromide, chloride (as Cl-): ≤300 mg/kg
iodate (IO3-): ≤2 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Fe: ≤5 mg/kg
K: ≤500 mg/kg

suitability

complies for appearance of solution

SMILES string

[Na+].[I-]

InChI

1S/HI.Na/h1H;/q;+1/p-1

InChI key

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

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General description

Sodium iodide is an inorganic salt. Mixture of chlorotrimethylsilane/sodium iodide in acetonitrile is a useful reagent for the cleavage of esters, lactones, carbamates and ethers.

Application

Sodium iodide may be used in the preparation of sodium hydroxide-sodium iodide reagent for the modified Winkler method for the determination of dissolved oxygen. It may be used for the synthesis of coppersensor-1 (CS1), a membrane-permeable fluorescent dye used for imaging labile copper pools in biological samples.

Caution

may contain black particle through the manufacture

Signal Word

Danger

Hazard Statements

H315 - H319 - H372 - H400

Hazard Classifications

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT RE 1 Oral

Target Organs

Thyroid

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Evan W Miller et al.
Nature protocols, 1(2), 824-827 (2007-04-05)
Coppersensor-1 (CS1) is a small-molecule, membrane-permeable fluorescent dye for imaging labile copper pools in biological samples, including live cells. This probe, comprising a boron dipyrromethene (BODIPY) chromophore coupled to a thioether-rich receptor, has a picomolar affinity for Cu+ with high
The Chesapeake Bay Institute technique for the Winkler dissolved oxygen method.
Carpenter JH.
Limnology and Oceanography, 10(1), 141-143 (1965)
Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent.
Olah GA, et al.
The Journal of Organic Chemistry, 44(8), 1247-1251 (1979)
Anke de Vries et al.
Investigative radiology, 50(4), 297-304 (2015-01-01)
The objective of this study was to investigate the feasibility and the accuracy of spectral computed tomography (spectral CT) to determine the tissue concentrations and localization of high-attenuation, iodine-based contrast agents in mice. Iodine tissue concentrations determined with spectral CT
Caroline Serrano-Nascimento et al.
Molecular and cellular endocrinology, 349(2), 154-161 (2011-10-18)
Iodide excess acutely downregulates NIS mRNA expression, as already demonstrated. PCCl3 cells treated or not with NaI, NaI+NaClO(4) or NaI+Methimazole, for 30 min to 24 h, were used to further explore how iodide reduces NIS gene expression. NIS mRNA expression
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