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Merck
CN

13204

β-tri-Calcium phosphate

puriss. p.a., ≥98% β-phase basis (unsintered powder)

Synonym(s):

β-TCP, β-Tricalcium phosphate

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About This Item

Empirical Formula (Hill Notation):
Ca3O8P2
CAS Number:
7758-87-4
Molecular Weight:
310.18
UNSPSC Code:
12352302
PubChem Substance ID:
329750099
EC Number:
231-840-8
NACRES:
NA.55
MDL number:
MFCD00015984
Assay:
≥98% β-phase basis (unsintered powder)
Form:
powder

Key Documents

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Product Name

β-tri-Calcium phosphate, puriss. p.a., ≥98% β-phase basis (unsintered powder)

SMILES string

[Ca+2].[Ca+2].[Ca+2].[P](=O)([O-])([O-])[O-].[P](=O)([O-])([O-])[O-]

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

grade

puriss. p.a.

assay

≥98% β-phase basis (unsintered powder)

form

powder

impurities

≤250 mg/kg total sulfur (as SO4) (ICP)
≤50 mg/kg total heavy metals (as lead)

anion traces

chloride (Cl-): ≤100 mg/L

cation traces

As: ≤0.5 mg/kg
Ba: ≤10 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤5 mg/kg
Cu: ≤1 mg/kg
Hg: ≤0.5 mg/kg
Ni: ≤1 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

Quality Level

200

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Analysis Note

Phase Composition (by XRD analysis)
Low crystalinity Hydroxylapatite at unsintered condition.
A high crystalinity ß-Tricalcium phosphate after sintering at 1100C.
ß-TCP: >98% (by x-ray diffraction analysis)
other Ca-P phases as Hydroxylapatite, a-TCP and Pyrophosphate <2.0%

General description

β-tri-Calcium phosphate belongs to the category of calcium-phosphate based ceramics, which has been involved in the preparation of a new biosynthetic material possessing morphogenetic activity that is used as a bone implant.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2088
BCCL4677
BCCF6631
BCCD4405
BCCB2536

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A new polyphosphate calcium material with morphogenetic activity
Muller.G.EW, et al.
Materials Letters, 148, 163-166 (2015)
Floor C J van de Watering et al.
Journal of controlled release : official journal of the Controlled Release Society, 164(3), 283-290 (2012-07-18)
Clinical application of calcium phosphate cement (CPC; with incorporated polymeric porogens) in an injectable form implicates that loading methods for growth factors are limited. In view of this, the current study evaluated the in vitro and in vivo release kinetics
A H Choi et al.
Journal of dental research, 92(10), 853-859 (2013-07-17)
The purpose of coatings on implants is to achieve some or all of the improvements in biocompatibility, bioactivity, and increased protection from the release of harmful or unnecessary metal ions. During the last decade, there has been substantially increased interest
Michael D Weiden et al.
PloS one, 9(10), e108476-e108476 (2014-10-02)
While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences derived from bronchoalveolar lavage (BAL) of aerosol IFN-γ-treated patients and induction of adenosine deaminase acting on RNA 1
A Butscher et al.
Acta biomaterialia, 9(2), 5369-5378 (2012-10-17)
Powder based three-dimensional printing (3DP) allows great versatility in material and geometry. These characteristics make 3DP an interesting method for the production of tissue engineering scaffolds. However, 3DP has major limitations, such as limited resolution and accuracy, hence preventing the
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