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Merck
CN

156264

Ammonium formate

reagent grade, 97%

Synonym(s):

Formic acid ammonium salt

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About This Item

Linear Formula:
HCO2NH4
CAS Number:
Molecular Weight:
63.06
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39021903
UNSPSC Code:
12352106
EC Number:
208-753-9
MDL number:
Beilstein/REAXYS Number:
3625095
Assay:
97%
Grade:
reagent grade
Form:
granular
moist crystals
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Product Name

Ammonium formate, reagent grade, 97%

InChI key

VZTDIZULWFCMLS-UHFFFAOYSA-N

InChI

1S/CH2O2.H3N/c2-1-3;/h1H,(H,2,3);1H3

SMILES string

N.OC=O

grade

reagent grade

assay

97%

form

granular
moist crystals

pH

5.5-7.5 (25 °C, 63.1 g/L)

mp

119-121 °C (lit.)

density

1.26 g/mL at 25 °C (lit.)

Quality Level

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Application

Ammonium formate may be employed in the following studies:
  • Deprotection of N-benzyl derivatives of amino acids and amines to afford free amino acids and amines.
  • Conversion of α, β-unsaturated nitroalkenes to the corresponding oximes.
  • Preparation of nitriles.

General description

Ammonium formate is an ammonium salt of formic acid. It is a cheap and promising N-formylating agent for various amines (secondary and aniline). Its anhydrous form may be employed as a catalyst for the synthesis of various amino derivatives from aliphatic and aromatic compounds.
Ammonium formate can be used as a source to produce ammonia. It can also be used in the reductive alkylation of amines.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Copper-Catalyzed Synthesis of Nitriles by Aerobic Oxidative Reaction of Alcohols and Ammonium Formate.
Yadav DKT and Bhanage BM.
European Journal of Organic Chemistry, 23, 5106-5110 (2013)
Trost.MB
Comprehensive Organic Synthesis, 8 (1991)
Appukkuttan P et al.
Microwave Methods in Organic Synthesis, 266 (2006)
The palladium assisted transfer reduction of a, ?-unsaturated nitroalkenes to oximes using ammonium formate.
Kabalka GW, et al.
Synthetic Communications, 20(16), 2453-2458 (1990)
A convenient method for the N-formylation of secondary amines and anilines using ammonium formate.
Reddy PG, et al.
Tetrahedron Letters, 41(47), 9149-9151 (2000)

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