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About This Item
Linear Formula:
CuSO4 · 5H2O
CAS Number:
Molecular Weight:
249.69
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-847-6
MDL number:
Assay:
≥98.0%, 98.0-102.0% (ACS specification)
Grade:
ACS reagent
Form:
crystals
grade
ACS reagent
Quality Level
vapor pressure
7.3 mmHg ( 25 °C)
assay
≥98.0%, 98.0-102.0% (ACS specification)
form
crystals
reaction suitability
reaction type: click chemistry, reagent type: catalyst
core: copper
pH
3.5-4.5 (20 °C, 50 g/L)
mp
110 °C (dec.) (lit.)
anion traces
chloride (Cl-): ≤0.001%
cation traces
Ca: ≤0.005%, Fe: ≤0.003%, K: ≤0.01%, Na: ≤0.02%, Ni: ≤0.005%
SMILES string
O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O
InChI
1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2
InChI key
JZCCFEFSEZPSOG-UHFFFAOYSA-L
General description
Copper(II) sulfate pentahydrate is a Lewis acid catalyst commonly used to promote acid-catalyzed organic transformations. It can also act as an effective redox catalyst in combination with other mixed oxidizing agents.
Application
Copper(II) sulfate pentahydrate can be used as a catalyst:
It can also be used as a template in the synthesis of copper(II) ion-imprinted polymers using vinylpyridine and methacrylic acid as functional monomers. This polymer is used to quantify Cu2+ ion by using flame atomic absorption spectroscopy.
- In acetylation of alcohols and phenols in the presence of acetic anhydride.
- To synthesize various ynamides via intramolecular coupling of amides with alkynyl bromides.
It can also be used as a template in the synthesis of copper(II) ion-imprinted polymers using vinylpyridine and methacrylic acid as functional monomers. This polymer is used to quantify Cu2+ ion by using flame atomic absorption spectroscopy.
Features and Benefits
CuSO4.5H2O is an inexpensive, safe catalyst to be used in various organic transformations. It can also be recovered and reused in another reaction.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
11 - Combustible Solids
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Copper (II) Sulfate.
Hoffman RV, et al.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
Copper (II) sulfate pentahydrate (CuSO4. 5H2O): a green catalyst for solventless acetylation of alcohols and phenols with acetic anhydride.
Heravi MM, et al.
Journal of the Brazilian Chemical Society, 17(5), 1045-1047 (2006)
Xuan Ming et al.
Cell research, 30(11), 980-996 (2020-06-26)
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity. Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question. A replication-coupled DNA methylation maintenance model was
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 209198-100G | 04061837768453 |
| 209198-2.5KG | 04061835346585 |
| 209198-5G | 04061837768484 |
| 209198-25KG | 04061833636473 |
| 209198-12KG | 04061838770592 |
| 209198-500G | 04061837768477 |
| 209198-250G | 04061837768460 |


