217565
Barium chloride dihydrate
ACS reagent, ≥99%
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About This Item
Empirical Formula (Hill Notation):
BaCl2 · 2H2O
CAS Number:
Molecular Weight:
244.26
NACRES:
NB.24
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
233-788-1
MDL number:
Assay:
≥99%
Grade:
ACS reagent
Form:
powder, crystals or chunks
grade
ACS reagent
Quality Level
assay
≥99%
form
powder, crystals or chunks
impurities
≤0.005% insolubles, ≤0.005% oxidizers
loss
14.0-16.0% loss on drying
pH
5.2-8.2 (25 °C, 5%)
cation traces
Ca: ≤0.05%, Fe: ≤2 ppm, K: ≤0.0025%, Na: ≤0.005%, Sr: ≤0.1%, heavy metals: ≤5 ppm (by ICP-OES)
SMILES string
O.O.Cl[Ba]Cl
InChI
1S/Ba.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2
InChI key
PWHCIQQGOQTFAE-UHFFFAOYSA-L
Application
Barium chloride dihydrate has been used:
- in patch-clamp electrophysiological studies to block subthreshold-activated potassium channels
- as an inward rectifier potassium (Kir) channel blocker to study the role of the channel by measuring the microglial membrane currents in response to voltage ramp stimuli after ATP injection
- to prepare the stock solution to make artificial cerebrospinal fluid (aCSF)
Biochem/physiol Actions
Barium chloride is a potassium ion channel blocker. It is considered toxic. Barium chloride prevents the D2-like receptor-mediated hyperpolarisation of spinal central pattern generator (CPG) neurons
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Irrit. 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
危险化学品
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Laurence D Picton et al.
Scientific reports, 6, 35749-35749 (2016-10-21)
Dopamine plays important roles in the development and modulation of motor control circuits. Here we show that dopamine exerts potent effects on the central pattern generator circuit controlling locomotory swimming in post-embryonic Xenopus tadpoles. Dopamine (0.5-100 μM) reduced fictive swim bout
Evaluation of quality changes in walnut kernels (Juglans regia L.) by Vis/NIR spectroscopy.
Jensen PN, et al.
Journal of Agricultural and Food Chemistry, 49(12), 5790-5796 (2001)
Proton magnetic resonance study of the structure of barium chloride dihydrate.
Silvidi AA and McGrath JW.
J. Chem. Phys. , 32(3), 924-926 (1960)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 217565-2.5KG | 04061838775009 |
| 217565-100G | 04061838774996 |
| 217565-500G | 04061834504818 |